Literature DB >> 18830511

A catalytic highly enantioselective direct synthesis of 2-bromo-2-nitroalkan-1-ols through a Henry reaction.

Gonzalo Blay1, Victor Hernández-Olmos, José R Pedro.   

Abstract

Highly enantiomerically enriched 2-bromo-2-nitroalkan-1-ols are prepared by direct condensation of aliphatic and aromatic aldehydes with bromonitromethane in the presence of a catalytic amount of copper(ii) acetate and a C(1)-symmetric camphor-derived amino pyridine ligand.

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Year:  2008        PMID： 18830511     DOI： 10.1039/b809739a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

1.  Rapid synthesis of cyclic oligomeric depsipeptides with positional, stereochemical, and macrocycle size distribution control.

Authors:  Suzanne M Batiste; Jeffrey N Johnston
Journal:  Proc Natl Acad Sci U S A       Date:  2016-12-14       Impact factor: 11.205

2.  Enantioselective Addition of Bromonitromethane to Aliphatic N-Boc Aldimines Using a Homogeneous Bifunctional Chiral Organocatalyst.

Authors:  Kenneth E Schwieter; Jeffrey N Johnston
Journal:  ACS Catal       Date:  2015       Impact factor: 13.084

3.  A convergent synthesis of 1,3,4-oxadiazoles from acyl hydrazides under semiaqueous conditions.

Authors:  Kazuyuki Tokumaru; Jeffrey N Johnston
Journal:  Chem Sci       Date:  2017-02-23       Impact factor: 9.825

Review 4.  Asymmetric catalysis in direct nitromethane-free Henry reactions.

Authors:  Lin Dong; Fen-Er Chen
Journal:  RSC Adv       Date:  2020-01-13       Impact factor: 4.036

5.  Novel camphor-based pyrimidine derivatives induced cancer cell death through a ROS-mediated mitochondrial apoptosis pathway.

Authors:  Yan Zhang; Yunyun Wang; Yuxun Zhao; Wen Gu; Yongqiang Zhu; Shifa Wang
Journal:  RSC Adv       Date:  2019-09-19       Impact factor: 4.036

6.  Rigid and concave, 2,4-cis-substituted azetidine derivatives: A platform for asymmetric catalysis.

Authors:  Akina Yoshizawa; Antonio Feula; Louise Male; Andrew G Leach; John S Fossey
Journal:  Sci Rep       Date:  2018-04-25       Impact factor: 4.379
  6 in total

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