Literature DB >> 18830507

Interaction of trivalent antimony with a CCHC zinc finger domain: potential relevance to the mechanism of action of antimonial drugs.

Cynthia Demicheli1, Frédéric Frézard, John B Mangrum, Nicholas P Farrell.   

Abstract

Sb(III) competes with Zn(II) for its binding to the CCHC zinc finger domain of the NCp7 protein of HIV-1, indicating that zinc finger proteins may be targets for antimony-based drugs and thus responsible for their important pharmacological actions.

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Year:  2008        PMID： 18830507     DOI： 10.1039/b809186b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  11 in total

Review 1.  Antimony transport mechanisms in resistant leishmania parasites.

Authors:  Frédéric Frézard; Rubens Monte-Neto; Priscila G Reis
Journal:  Biophys Rev       Date:  2014-01-25

2.  Characterization of the proliferating cell nuclear antigen of Leishmania donovani clinical isolates and its association with antimony resistance.

Authors:  Rati Tandon; Sharat Chandra; Rajendra Kumar Baharia; Sanchita Das; Pragya Misra; Awanish Kumar; Mohammad Imran Siddiqi; Shyam Sundar; Anuradha Dube
Journal:  Antimicrob Agents Chemother       Date:  2014-03-10       Impact factor: 5.191

3.  Synthesis and characterization of bismuth(III) and antimony(V) porphyrins: high antileishmanial activity against antimony-resistant parasite.

Authors:  Marcela Luísa Gomes; Gilson DeFreitas-Silva; Priscila Gomes dos Reis; Maria Norma Melo; Frédéric Frézard; Cynthia Demicheli; Ynara Marina Idemori
Journal:  J Biol Inorg Chem       Date:  2015-05-01       Impact factor: 3.358

Review 4.  Leishmania antimony resistance: what we know what we can learn from the field.

Authors:  Khatima Aït-Oudhia; Elodie Gazanion; Baptiste Vergnes; Bruno Oury; Denis Sereno
Journal:  Parasitol Res       Date:  2011-07-29       Impact factor: 2.289

5.  Cu(I) Disrupts the Structure and Function of the Nonclassical Zinc Finger Protein Tristetraprolin (TTP).

Authors:  Geoffrey D Shimberg; Kiwon Ok; Heather M Neu; Kathryn E Splan; Sarah L J Michel
Journal:  Inorg Chem       Date:  2017-05-30       Impact factor: 5.165

6.  Use of antimony in the treatment of leishmaniasis: current status and future directions.

Authors:  Arun Kumar Haldar; Pradip Sen; Syamal Roy
Journal:  Mol Biol Int       Date:  2011-06-08

Review 7.  Pentavalent antimonials: new perspectives for old drugs.

Authors:  Frédéric Frézard; Cynthia Demicheli; Raul R Ribeiro
Journal:  Molecules       Date:  2009-06-30       Impact factor: 4.411

8.  Interaction of Natural Compounds in Licorice and Turmeric with HIV-NCp7 Zinc Finger Domain: Potential Relevance to the Mechanism of Antiviral Activity.

Authors:  Runjing Wang; Yinyu Wei; Meiqin Wang; Pan Yan; Hongliang Jiang; Zhifeng Du
Journal:  Molecules       Date:  2021-06-10       Impact factor: 4.411

9.  Association of liposome-encapsulated trivalent antimonial with ascorbic acid: an effective and safe strategy in the treatment of experimental visceral leishmaniasis.

Authors:  Renata A O Castro; Neila M Silva-Barcellos; Carolina S A Licio; Janine B Souza; Míriam C Souza-Testasicca; Flávia M Ferreira; Mauricio A Batista; Denise Silveira-Lemos; Sandra L Moura; Frédéric Frézard; Simone A Rezende
Journal:  PLoS One       Date:  2014-08-08       Impact factor: 3.240

10.  The Effect of Ursolic Acid on Leishmania (Leishmania) amazonensis Is Related to Programed Cell Death and Presents Therapeutic Potential in Experimental Cutaneous Leishmaniasis.

Authors:  Eduardo S Yamamoto; Bruno L S Campos; Jéssica A Jesus; Márcia D Laurenti; Susan P Ribeiro; Esper G Kallás; Mariana Rafael-Fernandes; Gabriela Santos-Gomes; Marcelo S Silva; Deborah P Sessa; João H G Lago; Débora Levy; Luiz F D Passero
Journal:  PLoS One       Date:  2015-12-16       Impact factor: 3.240
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