Literature DB >> 18830491

Diaryl ether synthesis in supercritical carbon dioxide in batch and continuous flow modes.

Jin-Kyun Lee1, Matthew J Fuchter, Rachel M Williamson, Gary A Leeke, Edward J Bush, Ian F McConvey, Simon Saubern, John H Ryan, Andrew B Holmes.   

Abstract

A high yielding, batch mode synthesis of diaryl ethers and sulfides by an S(N)Ar fluoride-mediated process in scCO(2) has been developed; the use of a polymer-supported imidazolium fluoride reagent in batch mode led to the development of a fixed-bed continuous flow process, with high conversions.

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Year:  2008        PMID: 18830491     DOI: 10.1039/b808374f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Translation of microwave methodology to continuous flow for the efficient synthesis of diaryl ethers via a base-mediated S(N)Ar reaction.

Authors:  Charlotte Wiles; Paul Watts
Journal:  Beilstein J Org Chem       Date:  2011-10-04       Impact factor: 2.883

  1 in total

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