OBJECTIVE: To determine which computed tomographic findings are associated with high-risk thymic epithelial tumors and a poor prognosis. METHODS: Computed tomographic findings of thymic epithelial neoplasms were retrospectively evaluated in 75 patients diagnosed with thymic tumor between January 1997 and October 2003. We analyzed the correlation of the computed tomographic findings, histological subtype according to the World Health Organization classification, and the prognosis. RESULTS: There were 34 with type A approximately B1 tumor and 41 with type B2 approximately C tumor. On multiple regression analysis, vascular obliteration and a blunt sternum-anterior mediastinum angle were more frequent with thymic carcinoma than with thymoma. On multivariate analysis, pleural effusion and mediastinal fat infiltration on initial computed tomography had a significant impact on survival. CONCLUSIONS: Vascular obliteration and a blunt sternum-anterior mediastinum angle were predictive of thymic carcinoma. Pleural effusion and mediastinal fat infiltration were predictive of a poor prognosis.
OBJECTIVE: To determine which computed tomographic findings are associated with high-risk thymic epithelial tumors and a poor prognosis. METHODS: Computed tomographic findings of thymic epithelial neoplasms were retrospectively evaluated in 75 patients diagnosed with thymic tumor between January 1997 and October 2003. We analyzed the correlation of the computed tomographic findings, histological subtype according to the World Health Organization classification, and the prognosis. RESULTS: There were 34 with type A approximately B1 tumor and 41 with type B2 approximately C tumor. On multiple regression analysis, vascular obliteration and a blunt sternum-anterior mediastinum angle were more frequent with thymic carcinoma than with thymoma. On multivariate analysis, pleural effusion and mediastinal fat infiltration on initial computed tomography had a significant impact on survival. CONCLUSIONS: Vascular obliteration and a blunt sternum-anterior mediastinum angle were predictive of thymic carcinoma. Pleural effusion and mediastinal fat infiltration were predictive of a poor prognosis.
Authors: Daniel B Green; Sarah Eliades; Alan C Legasto; Gulce Askin; Jeffrey L Port; James F Gruden Journal: Eur Radiol Date: 2019-02-26 Impact factor: 5.315
Authors: Suyon Chang; Jin Hur; Dong Jin Im; Young Joo Suh; Yoo Jin Hong; Hye-Jeong Lee; Young Jin Kim; Kyunghwa Han; Dae Joon Kim; Chang Young Lee; Ha Young Shin; Byoung Wook Choi Journal: Eur Radiol Date: 2016-08-23 Impact factor: 5.315