OBJECTIVE: To evaluate the performance of 4 methods of measuring the extent of ground-glass opacities as a means of predicting the 5-year relapse-free survival of patients with peripheral nonsmall cell lung cancer (NSLC). METHODS: Ground-glass opacities on thin-section computed tomographic images of 120 peripheral NSLCs were measured at 7 medical institutions by the length, area, modified length, and vanishing ratio (VR) methods. The performance (Az) of each method in predicting the 5-year relapse-free survival was evaluated using receiver operating characteristic analysis. RESULTS: The mean Az value obtained by the length, area, modified length, and VR methods in the receiver operating characteristic analyses was 0.683, 0.702, 0.728, and 0.784, respectively. The differences between the mean Az value obtained by the VR method and by the other 3 methods were significant. CONCLUSIONS: Vanishing ratio method was the most accurate predictor of the 5-year relapse-free survival of patients with peripheral NSLC.
OBJECTIVE: To evaluate the performance of 4 methods of measuring the extent of ground-glass opacities as a means of predicting the 5-year relapse-free survival of patients with peripheral nonsmall cell lung cancer (NSLC). METHODS: Ground-glass opacities on thin-section computed tomographic images of 120 peripheral NSLCs were measured at 7 medical institutions by the length, area, modified length, and vanishing ratio (VR) methods. The performance (Az) of each method in predicting the 5-year relapse-free survival was evaluated using receiver operating characteristic analysis. RESULTS: The mean Az value obtained by the length, area, modified length, and VR methods in the receiver operating characteristic analyses was 0.683, 0.702, 0.728, and 0.784, respectively. The differences between the mean Az value obtained by the VR method and by the other 3 methods were significant. CONCLUSIONS: Vanishing ratio method was the most accurate predictor of the 5-year relapse-free survival of patients with peripheral NSLC.
Authors: Fabien Maldonado; Jennifer M Boland; Sushravya Raghunath; Marie Christine Aubry; Brian J Bartholmai; Mariza Deandrade; Thomas E Hartman; Ronald A Karwoski; Srinivasan Rajagopalan; Anne-Marie Sykes; Ping Yang; Eunhee S Yi; Richard A Robb; Tobias Peikert Journal: J Thorac Oncol Date: 2013-04 Impact factor: 15.609
Authors: Ernst Th Scholten; Colin Jacobs; Bram van Ginneken; Sarah van Riel; Rozemarijn Vliegenthart; Matthijs Oudkerk; Harry J de Koning; Nanda Horeweg; Mathias Prokop; Hester A Gietema; Willem P Th M Mali; Pim A de Jong Journal: Eur Radiol Date: 2014-10-07 Impact factor: 5.315