OBJECTIVE: To use a population-based approach to describe survival trends in patients diagnosed as having gastric or esophageal adenocarcinoma. PATIENTS AND METHODS: A population-based complete chart review of all inpatient and outpatient records, using the resources of the Rochester Epidemiology Project, was conducted in Olmsted County, Minnesota (population 124,277), a primarily rural county with one large urban area. All residents of Olmsted County who were diagnosed as having gastric or esophageal adenocarcinoma from January 1, 1971, through December 31, 2000, were included in the study. The main outcomes were median survival and 2-year and 5-year survival rates, by decade of diagnosis. RESULTS: From 1971 through 2000, median survival for patients with gastric adenocarcinoma (n=121) decreased from 5.5 months to 3.2 months, whereas median survival for patients with esophageal adenocarcinoma (n=65) increased from 8.5 months to 11.7 months. Decade of diagnosis was not significantly associated with patient survival for either gastric or esophageal adenocarcinoma (P>.05). There was no significant shift in stage of disease at diagnosis during the 30-year period for either gastric or esophageal adenocarcinoma (P>.05). CONCLUSION: No significant change has occurred in the survival rates of this patient population with gastric or esophageal adenocarcinoma, which is representative of the US white population.
OBJECTIVE: To use a population-based approach to describe survival trends in patients diagnosed as having gastric or esophageal adenocarcinoma. PATIENTS AND METHODS: A population-based complete chart review of all inpatient and outpatient records, using the resources of the Rochester Epidemiology Project, was conducted in Olmsted County, Minnesota (population 124,277), a primarily rural county with one large urban area. All residents of Olmsted County who were diagnosed as having gastric or esophageal adenocarcinoma from January 1, 1971, through December 31, 2000, were included in the study. The main outcomes were median survival and 2-year and 5-year survival rates, by decade of diagnosis. RESULTS: From 1971 through 2000, median survival for patients with gastric adenocarcinoma (n=121) decreased from 5.5 months to 3.2 months, whereas median survival for patients with esophageal adenocarcinoma (n=65) increased from 8.5 months to 11.7 months. Decade of diagnosis was not significantly associated with patient survival for either gastric or esophageal adenocarcinoma (P>.05). There was no significant shift in stage of disease at diagnosis during the 30-year period for either gastric or esophageal adenocarcinoma (P>.05). CONCLUSION: No significant change has occurred in the survival rates of this patient population with gastric or esophageal adenocarcinoma, which is representative of the US white population.
Authors: Winson Y Cheung; Rihong Zhai; Matthew H Kulke; Rebecca S Heist; Kofi Asomaning; Clement Ma; Zhaoxi Wang; Li Su; Michael Lanuti; Kenneth K Tanabe; David C Christiani; Geoffrey Liu Journal: Carcinogenesis Date: 2009-06-11 Impact factor: 4.944
Authors: Winson Y Cheung; Rihong Zhai; Penny Bradbury; Jessica Hopkins; Matthew H Kulke; Rebecca S Heist; Kofi Asomaning; Clement Ma; Wei Xu; Zhaoxi Wang; Suzanne Hooshmand; Li Su; David C Christiani; Geoffrey Liu Journal: Int J Cancer Date: 2012-04-24 Impact factor: 7.396
Authors: Rihong Zhai; Feng Chen; Geoffrey Liu; Li Su; Matthew H Kulke; Kofi Asomaning; Xihong Lin; Rebecca S Heist; Norman S Nishioka; Chau-Chyun Sheu; John C Wain; David C Christiani Journal: J Clin Oncol Date: 2010-04-12 Impact factor: 44.544
Authors: Muhammad A Alvi; Xinxue Liu; Maria O'Donovan; Richard Newton; Lorenz Wernisch; Nicholas B Shannon; Kareem Shariff; Massimiliano di Pietro; Jacques J G H M Bergman; Krish Ragunath; Rebecca C Fitzgerald Journal: Clin Cancer Res Date: 2012-12-14 Impact factor: 12.531