Literature DB >> 18828942

Contribution of economic evaluation to decision making in early phases of product development: a methodological and empirical review.

Susanne Hartz1, Jürgen John.   

Abstract

BACKGROUND: Economic evaluation as an integral part of health technology assessment is today mostly applied to established technologies. Evaluating healthcare innovations in their early states of development has recently attracted attention. Although it offers several benefits, it also holds methodological challenges.
OBJECTIVES: The aim of our study was to investigate the possible contributions of economic evaluation to industry's decision making early in product development and to confront the results with the actual use of early data in economic assessments.
METHODS: We conducted a literature research to detect methodological contributions as well as economic evaluations that used data from early phases of product development.
RESULTS: Economic analysis can be beneficially used in early phases of product development for various purposes including early market assessment, R&D portfolio management, and first estimations of pricing and reimbursement scenarios. Analytical tools available for these purposes have been identified. Numerous empirical works were detected, but most do not disclose any concrete decision context and could not be directly matched with the suggested applications.
CONCLUSIONS: Industry can benefit from starting economic evaluation early in product development in several ways. Empirical evidence suggests that there is still potential left unused.

Mesh:

Year:  2008        PMID: 18828942     DOI: 10.1017/S0266462308080616

Source DB:  PubMed          Journal:  Int J Technol Assess Health Care        ISSN: 0266-4623            Impact factor:   2.188


  11 in total

1.  The implementation of a noninvasive lymph node staging (NILS) preoperative prediction model is cost effective in primary breast cancer.

Authors:  Lisa Rydén; Ida Skarping; Kristoffer Nilsson; Looket Dihge; Adam Fridhammar; Mattias Ohlsson; Linnea Huss; Pär-Ola Bendahl; Katarina Steen Carlsson
Journal:  Breast Cancer Res Treat       Date:  2022-07-05       Impact factor: 4.624

2.  Early economic evaluation of emerging health technologies: protocol of a systematic review.

Authors:  Ba' Pham; Hong Anh Thi Tu; Dolly Han; Petros Pechlivanoglou; Fiona Miller; Valeria Rac; Warren Chin; Andrea C Tricco; Mike Paulden; Joanna Bielecki; Murray Krahn
Journal:  Syst Rev       Date:  2014-07-23

3.  Pharmacoeconomics.

Authors:  Dyfrig A Hughes
Journal:  Br J Clin Pharmacol       Date:  2012-06       Impact factor: 4.335

4.  Mechanism-based approach to the economic evaluation of pharmaceuticals: pharmacokinetic/pharmacodynamic/pharmacoeconomic analysis of rituximab for follicular lymphoma.

Authors:  Joshua Pink; Steven Lane; Dyfrig A Hughes
Journal:  Pharmacoeconomics       Date:  2012-05       Impact factor: 4.981

5.  HEADROOM APPROACH TO DEVICE DEVELOPMENT: CURRENT AND FUTURE DIRECTIONS.

Authors:  Alan Girling; Richard Lilford; Amanda Cole; Terry Young
Journal:  Int J Technol Assess Health Care       Date:  2015-12-23       Impact factor: 2.188

6.  A qualitative exploration of early assessment of innovative medical technologies.

Authors:  Iben Fasterholdt; Anne Lee; Kristian Kidholm; Knud Bonnet Yderstræde; Kjeld Møller Pedersen
Journal:  BMC Health Serv Res       Date:  2018-11-06       Impact factor: 2.655

7.  Stakeholder engagement in economic evaluation: Protocol for using the nominal group technique to elicit patient, healthcare provider, and health system stakeholder input in the development of an early economic evaluation model of chimeric antigen receptor T-cell therapy.

Authors:  Kednapa Thavorn; Justin Presseau; Mackenzie Wilson; Terry Hawrysh; Ian D Graham; Harold Atkins; Natasha Kekre; Doug Coyle; Manoj M Lalu; Dean A Fergusson; Kelvin Kw Chan; Daniel A Ollendorf
Journal:  BMJ Open       Date:  2021-08-12       Impact factor: 2.692

8.  Clearing up the hazy road from bench to bedside: a framework for integrating the fourth hurdle into translational medicine.

Authors:  Wolf H Rogowski; Susanne C Hartz; Jürgen H John
Journal:  BMC Health Serv Res       Date:  2008-09-24       Impact factor: 2.655

Review 9.  Emerging Use of Early Health Technology Assessment in Medical Product Development: A Scoping Review of the Literature.

Authors:  Maarten J IJzerman; Hendrik Koffijberg; Elisabeth Fenwick; Murray Krahn
Journal:  Pharmacoeconomics       Date:  2017-07       Impact factor: 4.981

Review 10.  Innovation at the Intersection of Clinical Trials and Real-World Data Science to Advance Patient Care.

Authors:  Brandon Swift; Lokesh Jain; Craig White; Vasu Chandrasekaran; Aman Bhandari; Dyfrig A Hughes; Pravin R Jadhav
Journal:  Clin Transl Sci       Date:  2018-05-16       Impact factor: 4.689

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