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Literature DB >> 18828583

Small molecule modulators of toll-like receptors.

Michael Czarniecki¹.

Abstract

Mesh：

Substances：

Year: 2008 PMID： 18828583 DOI： 10.1021/jm800957k

Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446

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13 in total

1. Toll-like receptor 4 plays a central role in cardiac dysfunction during trauma hemorrhage shock.

Authors: Xia Zhang; Chen Lu; Ming Gao; Xinyun Cao; Tuanzhu Ha; John H Kalbfleisch; David L Williams; Chuanfu Li; Race L Kao
Journal: Shock Date: 2014-07 Impact factor: 3.454

2. Discovery and Structure-Activity Relationships of the Neoseptins: A New Class of Toll-like Receptor-4 (TLR4) Agonists.

Authors: Matthew D Morin; Ying Wang; Brian T Jones; Lijing Su; Murali M R P Surakattula; Michael Berger; Hua Huang; Elliot K Beutler; Hong Zhang; Bruce Beutler; Dale L Boger
Journal: J Med Chem Date: 2016-04-25 Impact factor: 7.446

Review 3. Alkynoates as Versatile and Powerful Chemical Tools for the Rapid Assembly of Diverse Heterocycles under Transition-Metal Catalysis: Recent Developments and Challenges.

Authors: Imtiaz Khan; Aliya Ibrar; Sumera Zaib
Journal: Top Curr Chem (Cham) Date: 2021-01-05

4. Discovery of a novel TLR2 signaling inhibitor with anti-viral activity.

Authors: Shenghua Zhou; Anna M Cerny; Glennice Bowen; Melvin Chan; David M Knipe; Evelyn A Kurt-Jones; Robert W Finberg
Journal: Antiviral Res Date: 2010-07-23 Impact factor: 5.970

5. Synthesis, structure-activity relationship studies and evaluation of a TLR 3/8/9 agonist and its analogues.

Authors: Anindya Sarkar; Anushka C Galasiti Kankanamalage; Qian Zhang; Heng Cheng; Prasanna Sivaprakasam; Joseph Naglich; Chunshan Xie; Sanjeev Gangwar; Dale L Boger
Journal: Med Chem Res Date: 2021-05-18 Impact factor: 2.351

6. Theranostic Small-Molecule Prodrug Conjugates for Targeted Delivery and Controlled Release of Toll-like Receptor 7 Agonists.

Authors: Sashi Debnath; Guiyang Hao; Bing Guan; Pawan Thapa; Justin Hao; Hans Hammers; Xiankai Sun
Journal: Int J Mol Sci Date: 2022-06-28 Impact factor: 6.208

Small molecule modulators of toll-like receptors.

1. Toll-like receptor 4 plays a central role in cardiac dysfunction during trauma hemorrhage shock.

2. Discovery and Structure-Activity Relationships of the Neoseptins: A New Class of Toll-like Receptor-4 (TLR4) Agonists.

Review 3. Alkynoates as Versatile and Powerful Chemical Tools for the Rapid Assembly of Diverse Heterocycles under Transition-Metal Catalysis: Recent Developments and Challenges.

4. Discovery of a novel TLR2 signaling inhibitor with anti-viral activity.

5. Synthesis, structure-activity relationship studies and evaluation of a TLR 3/8/9 agonist and its analogues.

6. Theranostic Small-Molecule Prodrug Conjugates for Targeted Delivery and Controlled Release of Toll-like Receptor 7 Agonists.

7. Novel toll-like receptor 2 ligands for targeted pancreatic cancer imaging and immunotherapy.

8. Diprovocims: A New and Exceptionally Potent Class of Toll-like Receptor Agonists.

9. Discovery of Imidazoquinolines with Toll-Like Receptor 7/8 Independent Cytokine Induction.

10. Design, Synthesis and Structure-Activity Relationship Optimization of Lycorine Derivatives for HCV Inhibition.