| Literature DB >> 18827194 |
Olga Gil1, Cristina Vilaplana, Evelyn Guirado, Jorge Díaz, Neus Cáceres, Mahavir Singh, Pere-Joan Cardona.
Abstract
Gamma interferon responses of spleen cells in mice were examined during postchemotherapy relapse of intraperitoneally induced latent tuberculous infection. The mycobacterial extract RUTI, which prevented the relapse, significantly enhanced the immune responses to secreted and structural recombinant mycobacterial antigens, suggesting that RUTI-mediated protection was mediated by activated T cells.Entities:
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Year: 2008 PMID: 18827194 PMCID: PMC2583524 DOI: 10.1128/CVI.00255-08
Source DB: PubMed Journal: Clin Vaccine Immunol ISSN: 1556-679X