Literature DB >> 18824817

Maternal obesity and pregnancy.

Hemant K Satpathy1, Alfred Fleming, Donald Frey, Michael Barsoom, Chabi Satpathy, Jimmy Khandalavala.   

Abstract

Obesity is a global health problem that is increasing in prevalence. The World Health Organization characterizes obesity as a pandemic issue, with a higher prevalence in females than males. Thus, many pregnant patients are seen with high body mass index (BMI). Obesity during pregnancy is considered a high-risk state because it is associated with many complications. Compared with normal-weight patients, obese patients have a higher prevalence of infertility. Once they conceive, they have higher rate of early miscarriage and congenital anomalies, including neural tube defects. Besides the coexistence of preexisting diabetes mellitus and chronic hypertension, obese women are more likely to have pregnancy-induced hypertension, gestational diabetes, thromboembolism, macrosomia, and spontaneous intrauterine demises in the latter half of pregnancy. Obese women also require instrument or Cesarean section delivery more often than average-weight women. Following Cesarean section delivery, obese women have a higher incidence of wound infection and disruption. Irrespective of the delivery mode, children born to obese mothers have a higher incidence of macrosomia and associated shoulder dystocia, which can be highly unpredictable. In addition to being large at birth, children born to obese mothers are also more susceptible to obesity in adolescence and adulthood. Prevention is the best way to prevent this problem. As pregnancy is the worst time to lose weight, women with a high BMI should be encouraged to lose weight prior to conceiving. During preconception counseling, they should be educated about the complications associated with high a BMI. Obese women should also be screened for hypertension and diabetes mellitus. In early pregnancy, besides being watchful about the higher association of miscarriage, obese women should be screened with ultrasound for congenital anomalies around 18 to 22 weeks. The ultrasound should be repeated close to term to check on the estimated fetal weight to rule out macrosomia. Obese pregnant women are screened for gestational diabetes around 24 to 28 weeks. During the second half of pregnancy, one needs to closely watch for signs and symptoms of pregnancy-induced hypertension. Once in labor, an early anesthesia consultation is highly recommended irrespective of delivery mode. When Cesarean section is performed, many obstetricians prefer an incision above the pannus to avoid skin infection. However, the incision should be decided upon the discretion of the surgeon. Peripartum, special attention is given to avoid thromboembolism by using compression stockings and early ambulation.

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Mesh:

Year:  2008        PMID: 18824817     DOI: 10.3810/pgm.2008.09.1920

Source DB:  PubMed          Journal:  Postgrad Med        ISSN: 0032-5481            Impact factor:   3.840


  22 in total

1.  Pregnancy-induced hypertension caused by all-trans retinoic acid treatment in acute promyelocytic leukemia.

Authors:  Kui Song; Min Li
Journal:  Oncol Lett       Date:  2015-05-07       Impact factor: 2.967

2.  Up-regulation of Toll-like receptor 4/nuclear factor-kappaB signaling is associated with enhanced adipogenesis and insulin resistance in fetal skeletal muscle of obese sheep at late gestation.

Authors:  Xu Yan; Mei J Zhu; Wei Xu; Jun F Tong; Stephen P Ford; Peter W Nathanielsz; Min Du
Journal:  Endocrinology       Date:  2009-11-03       Impact factor: 4.736

3.  Effect of revised IOM weight gain guidelines on perinatal outcomes.

Authors:  Donna R Halloran; Terry C Wall; Camelia Guild; Aaron B Caughey
Journal:  J Matern Fetal Neonatal Med       Date:  2010-07-01

Review 4.  Maternal and neonatal outcome after laparoscopic adjustable gastric banding: a systematic review.

Authors:  L Vrebosch; S Bel; G Vansant; I Guelinckx; R Devlieger
Journal:  Obes Surg       Date:  2012-10       Impact factor: 4.129

Review 5.  Maternal-infant nutrition and development programming of offspring appetite and obesity.

Authors:  Mina Desai; Michael G Ross
Journal:  Nutr Rev       Date:  2020-12-01       Impact factor: 7.110

Review 6.  Racial/ethnic disparities in obstetric outcomes and care: prevalence and determinants.

Authors:  Allison S Bryant; Ayaba Worjoloh; Aaron B Caughey; A Eugene Washington
Journal:  Am J Obstet Gynecol       Date:  2010-01-12       Impact factor: 8.661

7.  Obesity trends and perinatal outcomes in black and white teenagers.

Authors:  Donna R Halloran; Nicole E Marshall; Robert M Kunovich; Aaron B Caughey
Journal:  Am J Obstet Gynecol       Date:  2012-09-28       Impact factor: 8.661

Review 8.  Effect of atypical antipsychotics on fetal growth: is the placenta involved?

Authors:  Sandeep Raha; Valerie H Taylor; Alison C Holloway
Journal:  J Pregnancy       Date:  2012-07-11

9.  Obstetrical Management of an Extremely Overweight Pregnant Woman (184 kg bw) with Special Attention on Thromboprophylaxis.

Authors:  Boldizsar Horváth; Judit Skrapits; József Bódis
Journal:  Case Rep Obstet Gynecol       Date:  2013-03-04

10.  Obesity in pregnancy in southeast Nigeria.

Authors:  Co Chigbu; Lo Aja
Journal:  Ann Med Health Sci Res       Date:  2011-07
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