Literature DB >> 18824352

Inhibition of Candida albicans isocitrate lyase activity by sesterterpene sulfates from the tropical sponge Dysidea sp.

Dongha Lee1, Jongheon Shin, Kyung-Mi Yoon, Tae-Im Kim, So-Hyoung Lee, Hyi-Seung Lee, Ki-Bong Oh.   

Abstract

Seven sesterterpene sulfates (1-7) were isolated from the tropical sponge Dysidea sp. and their inhibitory activities against isocitrate lyase (ICL) from Candida albicans were evaluated. Among the isolated natural products compound 6 and 7 were found to be strong ICL inhibitors. The isolated compounds (1-7) also showed potent antibacterial effect against Bacillus subtilis and Proteus vulgaris, but did not display antifungal activity.

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Year:  2008        PMID： 18824352     DOI： 10.1016/j.bmcl.2008.09.059

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  5 in total

Review 1.  Antimicrobial Lipids from Plants and Marine Organisms: An Overview of the Current State-of-the-Art and Future Prospects.

Authors:  Eliana Alves; Marina Dias; Diana Lopes; Adelaide Almeida; Maria do Rosário Domingues; Felisa Rey
Journal:  Antibiotics (Basel)       Date:  2020-07-24

2.  Inhibition of Paracoccidioides lutzii Pb01 isocitrate lyase by the natural compound argentilactone and its semi-synthetic derivatives.

Authors:  Renata Silva do Prado; Ricardo Justino Alves; Cecília Maria Alves de Oliveira; Lucília Kato; Roosevelt Alves da Silva; Guilherme Oliveira Quintino; Silvio do Desterro Cunha; Célia Maria de Almeida Soares; Maristela Pereira
Journal:  PLoS One       Date:  2014-04-21       Impact factor: 3.240

3.  Suvanine sesterterpenes from a tropical sponge Coscinoderma sp. inhibit isocitrate lyase in the glyoxylate cycle.

Authors:  So-Hyoung Lee; Tae Hyung Won; Heegyu Kim; Chan-Hong Ahn; Jongheon Shin; Ki-Bong Oh
Journal:  Mar Drugs       Date:  2014-10-10       Impact factor: 5.118

Review 4.  Marine pharmacology in 2007-8: Marine compounds with antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, antituberculosis, and antiviral activities; affecting the immune and nervous system, and other miscellaneous mechanisms of action.

Authors:  Alejandro M S Mayer; Abimael D Rodríguez; Roberto G S Berlinck; Nobuhiro Fusetani
Journal:  Comp Biochem Physiol C Toxicol Pharmacol       Date:  2010-09-15       Impact factor: 3.228

Review 5.  Potential inhibitors for isocitrate lyase of Mycobacterium tuberculosis and non-M. tuberculosis: a summary.

Authors:  Yie-Vern Lee; Habibah A Wahab; Yee Siew Choong
Journal:  Biomed Res Int       Date:  2015-01-08       Impact factor: 3.411
  5 in total

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