Prenylated isoflavones from Flemingia philippinensis.

Two new prenylated isoflavones, named flemiphilippinins E and F, were isolated from the roots of Flemingia philippinensis, together with six known ones. The structures of the above compounds were established by spectroscopic methods. Flemiphilippinins E and F were identified as 5,4'-dihydroxy-8-(3,3-dimethylallyl)-6'',6''-dimethyl-5''-(1,1-dimethylallyl) pyrano(2'',3'':7,6)isoflavone and 5,4'-dihydroxy-4'',4'',5''-trimethyl-4'',5''-dihydrofurano(2'',3'':7,8) isoflavone, respectively, by a combination of HR-EI-MS, (1)H NMR, (13)C NMR, HMQC, HMBC, and NOESY spectra. Copyright (c) 2008 John Wiley & Sons, Ltd.