Literature DB >> 18820059

Cloning and characterization of alpha-methylacyl coenzyme A racemase from Gordonia polyisoprenivorans VH2.

Quyen Arenskötter1, Jens Heller, David Dietz, Matthias Arenskötter, Alexander Steinbüchel.   

Abstract

The mcr gene of Gordonia polyisoprenivorans VH2 is not clustered with genes required for rubber degradation. Its disruption by insertion of a kanamycin resistance cassette impaired growth on methyl-branched isoprenoids but not on linear hydrocarbons. Intact mcr from this bacterium or from Nocardia farcinica IFM 10152 complemented the mutant. Reverse transcription analysis showed similar mcr(VH2) expression results during cultivation with poly(cis-1,4-isoprene) and propionate. Additional genes coding for a putative cytochrome P450 monooxygenase and a short-chain dehydrogenase/reductase involved in beta-oxidation and poly(cis-1,4-isoprene) degradation were also characterized.

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Year:  2008        PMID： 18820059      PMCID： PMC2583472          DOI： 10.1128/AEM.01491-08

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  28 in total

1.  Directional genome walking using PCR.

Authors:  R N Mishra; S L Singla-Pareek; S Nair; S K Sopory; M K Reddy
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2.  Biotransformation of eugenol to vanillin by a mutant of Pseudomonas sp. strain HR199 constructed by disruption of the vanillin dehydrogenase (vdh) gene.

Authors:  J Overhage; H Priefert; J Rabenhorst; A Steinbüchel
Journal:  Appl Microbiol Biotechnol       Date:  1999-11       Impact factor: 4.813

3.  Fibroblast studies documenting a case of peroxisomal 2-methylacyl-CoA racemase deficiency: possible link between racemase deficiency and malabsorption and vitamin K deficiency.

Authors:  P P Van Veldhoven; E Meyhi; R H Squires; M Fransen; B Fournier; V Brys; M J Bennett; G P Mannaerts
Journal:  Eur J Clin Invest       Date:  2001-08       Impact factor: 4.686

4.  alpha-Methylacyl coenzyme A racemase as a tissue biomarker for prostate cancer.

Authors:  Mark A Rubin; Ming Zhou; Saravana M Dhanasekaran; Sooryanarayana Varambally; Terrence R Barrette; Martin G Sanda; Kenneth J Pienta; Debashis Ghosh; Arul M Chinnaiyan
Journal:  JAMA       Date:  2002-04-03       Impact factor: 56.272

5.  The role of alpha-methylacyl-CoA racemase in bile acid synthesis.

Authors:  Dean A Cuebas; Christopher Phillips; Werner Schmitz; Ernst Conzelmann; Dmitry K Novikov
Journal:  Biochem J       Date:  2002-05-01       Impact factor: 3.857

Review 6.  beta-oxidation - strategies for the metabolism of a wide variety of acyl-CoA esters.

Authors:  J K Hiltunen; Y Qin
Journal:  Biochim Biophys Acta       Date:  2000-04-12

Review 7.  The enzymes, regulation, and genetics of bile acid synthesis.

Authors:  David W Russell
Journal:  Annu Rev Biochem       Date:  2003-01-16       Impact factor: 23.643

8.  Liver disease caused by failure to racemize trihydroxycholestanoic acid: gene mutation and effect of bile acid therapy.

Authors:  Kenneth D R Setchell; James E Heubi; Kevin E Bove; Nancy C O'Connell; Tracy Brewsaugh; Steven J Steinberg; Ann Moser; Robert H Squires
Journal:  Gastroenterology       Date:  2003-01       Impact factor: 22.682

9.  Secretion and transcriptional regulation of the latex-clearing protein, Lcp, by the rubber-degrading bacterium Streptomyces sp. strain K30.

Authors:  Meral Yikmis; Matthias Arenskötter; Karsten Rose; Nicole Lange; Henrike Wernsmann; Lars Wiefel; Alexander Steinbüchel
Journal:  Appl Environ Microbiol       Date:  2008-07-07       Impact factor: 4.792

10.  Identification and application of plasmids suitable for transfer of foreign DNA to members of the genus Gordonia.

Authors:  Matthias Arenskötter; Dirk Baumeister; Rainer Kalscheuer; Alexander Steinbüchel
Journal:  Appl Environ Microbiol       Date:  2003-08       Impact factor: 4.792
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  4 in total

1.  Insights into the microbial degradation of rubber and gutta-percha by analysis of the complete genome of Nocardia nova SH22a.

Authors:  Quan Luo; Sebastian Hiessl; Anja Poehlein; Rolf Daniel; Alexander Steinbüchel
Journal:  Appl Environ Microbiol       Date:  2014-04-18       Impact factor: 4.792

2.  Involvement of two latex-clearing proteins during rubber degradation and insights into the subsequent degradation pathway revealed by the genome sequence of Gordonia polyisoprenivorans strain VH2.

Authors:  Sebastian Hiessl; Jörg Schuldes; Andrea Thürmer; Tobias Halbsguth; Daniel Bröker; Angel Angelov; Wolfgang Liebl; Rolf Daniel; Alexander Steinbüchel
Journal:  Appl Environ Microbiol       Date:  2012-02-10       Impact factor: 4.792

3.  Streptomyces sp. AC04842: Genomic Insights and Functional Expression of Its Latex Clearing Protein Genes (lcp1 and lcp2) When Cultivated With Natural and Vulcanized Rubber as the Sole Carbon Source.

Authors:  Ann Anni Basik; Chanaporn Trakunjae; Tiong Chia Yeo; Kumar Sudesh
Journal:  Front Microbiol       Date:  2022-05-02       Impact factor: 6.064

4.  Microbial gutta-percha degradation shares common steps with rubber degradation by Nocardia nova SH22a.

Authors:  Quan Luo; Sebastian Hiessl; Anja Poehlein; Alexander Steinbüchel
Journal:  Appl Environ Microbiol       Date:  2012-12-07       Impact factor: 4.792
  4 in total

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