BACKGROUND: Pregnancy is associated with down-regulation of immune responses of the mother. This might lead to reactivation and vertical transmission of latent viral infections such as BK virus (BKV). OBJECTIVES: To determine the presence of BKV in the urine of pregnant women and in cord blood at delivery. STUDY DESIGN: We examined urines from 52 pregnant women and 51 cord blood samples for BKV by real-time SYBR green PCR. RESULTS: BKV DNA was found in the urine of 18 (34.6%) pregnant women. No BKV DNA was detected by SYBR green PCR in the cord blood specimens. CONCLUSIONS: BKV reactivation is common during pregnancy but this is not associated with BKV in cord blood.
BACKGROUND: Pregnancy is associated with down-regulation of immune responses of the mother. This might lead to reactivation and vertical transmission of latent viral infections such as BK virus (BKV). OBJECTIVES: To determine the presence of BKV in the urine of pregnant women and in cord blood at delivery. STUDY DESIGN: We examined urines from 52 pregnant women and 51 cord blood samples for BKV by real-time SYBR green PCR. RESULTS:BKV DNA was found in the urine of 18 (34.6%) pregnant women. No BKV DNA was detected by SYBR green PCR in the cord blood specimens. CONCLUSIONS:BKV reactivation is common during pregnancy but this is not associated with BKV in cord blood.
Authors: Courtney L Kling; Alexandra T Wright; Sophie E Katz; Gloria B McClure; J Suzette Gardner; Jason T Williams; Natalie M Meinerz; Robert L Garcea; John A Vanchiere Journal: J Med Virol Date: 2012-09 Impact factor: 2.327
Authors: Roisin M Lonergan; Michael J Carr; Cillian F De Gascun; Lisa F Costelloe; Allison Waters; Suzie Coughlan; Marguerite Duggan; Katie Doyle; Sinead Jordan; Michael W Hutchinson; William W Hall; Niall J Tubridy Journal: J Neurovirol Date: 2009-09 Impact factor: 2.643
Authors: Ana Luisa Figueira Gouvêa; Rachel Ingrid Juliboni Cosendey; Ana Lucia Rosa Nascimento; Fabiana Rabe Carvalho; Andrea Alice Silva; Heleno Pinto de Moraes; Mayra Carrijo Rochael; Rafael Brandão Varella; Stephanie Gomes Almeida; Jorge Reis Almeida; Jocemir Ronaldo Lugon Journal: J Med Case Rep Date: 2017-05-24