| Literature DB >> 18818075 |
Mui Cheung1, Philip A Harris, Jennifer G Badiang, Gregory E Peckham, Stanley D Chamberlain, Michael J Alberti, David K Jung, Stephanie S Harris, Neal H Bramson, Andrea H Epperly, Stephen A Stimpson, Michael R Peel.
Abstract
A series of pyrazolo[1,5-a]pyridine derivatives was designed and synthesized as novel potent p38 kinase inhibitors. Our approaches towards improving in vitro metabolism and in vivo pharmacokinetic properties of the series are described.Entities:
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Year: 2008 PMID： 18818075 DOI： 10.1016/j.bmcl.2008.09.040
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823