Literature DB >> 18816524

Alkaloids from the roots of Zanthoxylum nitidum and their antiviral and antifungal effects.

Guohong Yang1, Daofeng Chen.   

Abstract

Five alkaloids, 5,6-dihydro-6-methoxynitidine (1), dictamnine (2), gamma-fagarine (3), skimmianine (4), and 5-methoxydictamnine (5), were isolated from the roots of Zanthoxylum nitidum. Their structures and configurations were elucidated by spectroscopic methods and X-ray analysis. Compounds 1, 4, and 5 showed in vitro antiviral effect against hepatitis B virus, and compounds 2, 3, and 5 demonstrated marked antimitotic and antifungal activity.

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Year:  2008        PMID： 18816524     DOI： 10.1002/cbdv.200890160

Source DB:  PubMed          Journal:  Chem Biodivers        ISSN： 1612-1872            Impact factor:   2.408


  5 in total

1.  Determination of quality markers for quality control of Zanthoxylum nitidum using ultra-performance liquid chromatography coupled with near infrared spectroscopy.

Authors:  Xinhong Wang; Qingwen Wu; Lulu Li; Peng Wang; Yue Wang; Weifeng Wei; Xiaojun Ma; Jing Shu; Kai Zhang; Dongming Ma
Journal:  PLoS One       Date:  2022-06-24       Impact factor: 3.752

2.  Metabolic Profile of Skimmianine in Rats Determined by Ultra-Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Tandem Mass Spectrometry.

Authors:  Aihua Huang; Hui Xu; Ruoting Zhan; Weiwen Chen; Jiawei Liu; Yuguang Chi; Daidi Chen; Xiaoyu Ji; Chaoquan Luo
Journal:  Molecules       Date:  2017-03-23       Impact factor: 4.411

3.  Analgesic Effect of Zanthoxylum nitidum Extract in Inflammatory Pain Models Through Targeting of ERK and NF-κB Signaling.

Authors:  Fenfen Qin; Han Zhang; Anlong Liu; Qisheng Wang; Qinmei Sun; Shengfeng Lu; Qian Li; Hongwei Guo; Xing Liu; Zhigang Lu
Journal:  Front Pharmacol       Date:  2019-04-24       Impact factor: 5.810

4.  Profiling and Pharmacokinetic Studies of Alkaloids in Rats After Oral Administration of Zanthoxylum nitidum Decoction by UPLC-Q-TOF-MS/MS and HPLC-MS/MS.

Authors:  Aihua Huang; Yuguang Chi; Jiawei Liu; Mincun Wang; Jialiang Qin; Lijuan Ou; Weiwen Chen; Zhongxiang Zhao; Ruoting Zhan; Hui Xu
Journal:  Molecules       Date:  2019-02-07       Impact factor: 4.411

5.  Dictamnine Inhibits the Adhesion to and Invasion of Uropathogenic Escherichia Coli (UPEC) to Urothelial Cells.

Authors:  Wenbo Yang; Peng Liu; Ying Chen; Qingyu Lv; Zhongtian Wang; Wenhua Huang; Hua Jiang; Yuling Zheng; Yongqiang Jiang; Liping Sun
Journal:  Molecules       Date:  2022-01-02       Impact factor: 4.411
  5 in total

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