Literature DB >> 1881586

Neutrophil as a mediator of ischemic edema formation in the brain.

Y Shiga1, H Onodera, K Kogure, Y Yamasaki, Y Yashima, H Syozuhara, F Sendo.   

Abstract

We investigated the contribution of neutrophils to brain edema formation using a transient focal ischemia model in rats. Rats were given anti-neutrophil monoclonal antibody (RP3) intraperitoneally to deplete circulating neutrophils. In RP3-treated rats, ischemic brain edema formation 1 day after reperfusion was significantly decreased compared to that of saline-treated control rats. We speculate that chemical mediators released by infiltrating neutrophils alter vascular permeability and play an important role in post-ischemic brain edema formation.

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Year:  1991        PMID： 1881586     DOI： 10.1016/0304-3940(91)90003-c

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  12 in total

Review 1.  Molecular dialogs between the ischemic brain and the peripheral immune system: dualistic roles in injury and repair.

Authors:  Chengrui An; Yejie Shi; Peiying Li; Xiaoming Hu; Yu Gan; Ruth A Stetler; Rehana K Leak; Yanqin Gao; Bao-Liang Sun; Ping Zheng; Jun Chen
Journal:  Prog Neurobiol       Date:  2013-12-26       Impact factor: 11.685

Review 2.  Role of blood cells in ischaemia-reperfusion induced endothelial barrier failure.

Authors:  Stephen F Rodrigues; D Neil Granger
Journal:  Cardiovasc Res       Date:  2010-03-17       Impact factor: 10.787

Review 3.  Cellular connections, microenvironment and brain angiogenesis in diabetes: Lost communication signals in the post-stroke period.

Authors:  Adviye Ergul; John Paul Valenzuela; Abdelrahman Y Fouda; Susan C Fagan
Journal:  Brain Res       Date:  2015-03-03       Impact factor: 3.252

4.  Expression of TNF and TNF receptors (p55 and p75) in the rat brain after focal cerebral ischemia.

Authors:  G I Botchkina; M E Meistrell; I L Botchkina; K J Tracey
Journal:  Mol Med       Date:  1997-11       Impact factor: 6.354

5.  Neutrophil and Platelet Activity and Quantification Following Delayed tPA Therapy in a Rabbit Model of Thromboembolic Stroke.

Authors: 
Journal:  J Thromb Thrombolysis       Date:  1995       Impact factor: 2.300

6.  Anti-neutrophil antibody enhances the neuroprotective effects of G-CSF by decreasing number of neutrophils in hypoxic ischemic neonatal rat model.

Authors:  Desislava M Doycheva; Tiffany Hadley; Li Li; Richard L Applegate; John H Zhang; Jiping Tang
Journal:  Neurobiol Dis       Date:  2014-05-27       Impact factor: 5.996

7.  Leg ischaemia before circulatory arrest alters brain leucocyte count and respiratory chain redox state.

Authors:  Fredrik S Yannopoulos; Oiva Arvola; Henri Haapanen; Johanna Herajärvi; Ilkka Miinalainen; Hanna Jensen; Kai Kiviluoma; Tatu Juvonen
Journal:  Interact Cardiovasc Thorac Surg       Date:  2013-12-16

Review 8.  Role of transcription factors in mediating post-ischemic cerebral inflammation and brain damage.

Authors:  Jae-Hyuk Yi; Seung-Won Park; Ramya Kapadia; Raghu Vemuganti
Journal:  Neurochem Int       Date:  2007-05-03       Impact factor: 3.921

9.  High doses of methylprednisolone are required for the treatment of collagenase-induced intracerebral hemorrhage in rats.

Authors:  Pablo Patricio Lema; Christiane Girard; Pascal Vachon
Journal:  Can J Vet Res       Date:  2005-10       Impact factor: 1.310

Review 10.  Role of Interleukin-1 Receptor-Like 1 (ST2) in Cerebrovascular Disease.

Authors:  Cristina Sastre; Matthew B Bevers; W Taylor Kimberly
Journal:  Neurocrit Care       Date:  2021-07-06       Impact factor: 3.210
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