| Literature DB >> 18813400 |
Tae-Joon Jeon1, Jason L Poulos, Jacob J Schmidt.
Abstract
The fragility and short lifetimes characteristic of conventionally formed lipid bilayer membranes has necessitated their preparation to be at the time and point of use. By using high freezing-point lipid-solvent mixtures, the process of lipid bilayer self-assembly may be reversibly arrested. In solid form, the bilayer precursor can be stored indefinitely and is sufficiently robust to withstand commercial shipping. Upon thawing, bilayer self-assembly resumes, resulting in a biologically functional membrane. Combination of this membrane precursor with an inexpensive chip results in a compact, practical, and disposable platform for ion channel measurements.Entities:
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Year: 2008 PMID: 18813400 DOI: 10.1039/b807932c
Source DB: PubMed Journal: Lab Chip ISSN: 1473-0189 Impact factor: 6.799