Literature DB >> 18812046

Factors contributing to treatment success among tuberculosis patients: a prospective cohort study in Bangkok.

K Okanurak1, D Kitayaporn, P Akarasewi.   

Abstract

SETTING: Chest Clinic, Ministry of Public Health and health care centres, Bangkok Metropolitan Administration.
OBJECTIVE: To determine patient factors predicting successful tuberculosis (TB) treatment.
DESIGN: A prospective cohort was conducted during May 2004 to November 2005. Newly diagnosed TB patients aged > or = 15 years were recruited after giving informed consent. Three sets of questionnaires were used to collect data from the patients three times. Data were also gathered from treatment cards.
RESULTS: Of 1241 patients, 81.1% were successfully treated. Bivariate analysis indicated that patients' sex, education, occupation, level of knowledge about TB and adverse effects were associated with treatment success. Unconditional logistic regression analysis showed that females had a higher success rate than males (OR = 1.9, 95%CI 1.2-2.9). Patients with regular incomes had twice the likelihood of success of the unemployed (OR = 2.0, 95%CI 1.1-3.5). Patients with high knowledge levels were more likely to complete treatment (OR = 2.0, 95%CI 1.2-3.4), while those with adverse effects were less likely to adhere (OR = 0.6, 95%CI 0.4-0.9).
CONCLUSION: The current low treatment success rate may be partly due to inadequate knowledge about TB among patients. Improvements in health education and early detection and management of adverse effects should be prioritised by the National Tuberculosis Programme.

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Year:  2008        PMID: 18812046

Source DB:  PubMed          Journal:  Int J Tuberc Lung Dis        ISSN: 1027-3719            Impact factor:   2.373


  9 in total

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Journal:  Epidemiol Infect       Date:  2017-02-13       Impact factor: 4.434

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7.  Association of PXR and CAR Polymorphisms and Antituberculosis Drug-Induced Hepatotoxicity.

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8.  Adherence to tuberculosis therapy among patients receiving home-based directly observed treatment: evidence from the United Republic of Tanzania.

Authors:  Abdallah Mkopi; Nyagosya Range; Fred Lwilla; Saidi Egwaga; Alexander Schulze; Eveline Geubbels; Frank van Leth
Journal:  PLoS One       Date:  2012-12-19       Impact factor: 3.240

9.  Determinants of Default from Tuberculosis Treatment among Patients with Drug-Susceptible Tuberculosis in Karachi, Pakistan: A Mixed Methods Study.

Authors:  Natasha Chida; Zara Ansari; Hamidah Hussain; Maria Jaswal; Stephen Symes; Aamir J Khan; Shama Mohammed
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  9 in total

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