Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Excessive blinking as an initial manifestation of juvenile Huntington's disease.

Literature DB >> 18810605

Excessive blinking as an initial manifestation of juvenile Huntington's disease.

Shihui Xing¹, Ling Chen, Xi Chen, Zhong Pei, Jinsheng Zeng, Jinru Li.

Abstract

Juvenile Huntington's disease (JHD) is mostly characterized by rigidity, myoclonus, bradykinesia, dystonia and seizure. We report a 9-year-old male JHD patient presenting excessive blinking as the initial symptom two years prior to typical JHD symptoms. Genetic analysis revealed expansion of 108 CAG repeats and magnetic resonance imaging showed caudate atrophy with lateral ventricular enlargement.

Entities: Disease Species

Mesh：

Substances：

Year: 2008 PMID： 18810605 DOI： 10.1007/s10072-008-0981-7

Source DB: PubMed Journal: Neurol Sci ISSN： 1590-1874 Impact factor: 3.307

15 in total

1. Increased blink rate in advanced Parkinson's disease: a form of 'off'-period dystonia?

Authors: T E Kimber; P D Thompson
Journal: Mov Disord Date: 2000-09 Impact factor: 10.338

2. The relationship between eye-winking tics, frequent eye-blinking and blepharospasm.

Authors: J S Elston; F C Granje; A J Lees
Journal: J Neurol Neurosurg Psychiatry Date: 1989-04 Impact factor: 10.154

3. Blink rates in Huntington's disease.

Authors: P Davous
Journal: Neurology Date: 1985-03 Impact factor: 9.910

4. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

Authors:
Journal: Cell Date: 1993-03-26 Impact factor: 41.582

Review 3. An Eye on Movement Disorders.

Authors: Duncan Wilson; Mark Hallett; Tim Anderson
Journal: Mov Disord Clin Pract Date: 2021-08-10

Review 4. Tics as an initial manifestation of juvenile Huntington's disease: case report and literature review.

Authors: Shi-Shuang Cui; Ru-Jing Ren; Ying Wang; Gang Wang; Sheng-Di Chen
Journal: BMC Neurol Date: 2017-08-08 Impact factor: 2.474

Review 5. Eyelid Dysfunction in Neurodegenerative, Neurogenetic, and Neurometabolic Disease.

Authors: Ali G Hamedani; Daniel R Gold
Journal: Front Neurol Date: 2017-07-18 Impact factor: 4.003

5 in total

Excessive blinking as an initial manifestation of juvenile Huntington's disease.

1. Increased blink rate in advanced Parkinson's disease: a form of 'off'-period dystonia?

2. The relationship between eye-winking tics, frequent eye-blinking and blepharospasm.

3. Blink rates in Huntington's disease.

4. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

5. Juvenile Huntington disease.

6. Relative efficacy of haloperidol and pimozide in children and adolescents with Tourette's disorder.

7. A prevalence study of primary dystonia in eight European countries.

8. Neurophysiological abnormalities in the Westphal variant of Huntington's disease.

Review 9. Huntington disease: clinical, genetic, and social aspects.

10. Blepharospasm and orofacial-cervical dystonia: clinical and pharmacological findings in 100 patients.

1. Reflexive and volitional saccades: biomarkers of Huntington disease severity and progression.

2. A Curious Case of Excessive Winking.

Review 3. An Eye on Movement Disorders.

Review 4. Tics as an initial manifestation of juvenile Huntington's disease: case report and literature review.

Review 5. Eyelid Dysfunction in Neurodegenerative, Neurogenetic, and Neurometabolic Disease.