Literature DB >> 18810514

T-cell lymphoma mimicking schwannoma of a cervical nerve root.

D Wachter1, S Tschischka, M Huegens-Penzel, K Kuchelmeister, R M Bohle, D-K Böker, U Nestler.   

Abstract

T-cell lymphoblastic lymphoma is a rare form of non-Hodgkin lymphoma, which shows preponderance for young men. Most common symptoms are painless swelling of lymph nodes, accompanied by B symptoms and large mediastinal masses. Most often, an involvement of the nervous system is due to paraneoplastic symptoms or side effects of treatment. In a literature research, we could not find a case with affection of a cervical nerve root as the first symptom for T-cell lymphoblastic lymphoma. A 39-year-old man presented with right-sided C8 radiculopathy, including pareses and paresthesia. Since the magnetic resonance image disclosed a right-sided mass lesion in the region of the neuroforamen C8, compressing the corresponding nerve root, a schwannoma was suspected. The tumor was removed using a dorsal approach. Neuropathological examination revealed the diagnosis of T-cell lymphoblastic lymphoma. The patient underwent diagnostic staging and received further treatment. He experienced a very grim course and succumbed to his disease 12 months after surgery. T-cell lymphoblastic lymphoma is a rare disease, and tropism of lymphoma cells to neural structures is seldom encountered. However, the presence of radiculopathy, together with signs, referring to B symptoms, should prompt the physician to consider this coincidence in the differential diagnosis of schwannoma.

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Year:  2008        PMID: 18810514     DOI: 10.1007/s10143-008-0169-x

Source DB:  PubMed          Journal:  Neurosurg Rev        ISSN: 0344-5607            Impact factor:   3.042


  12 in total

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2.  Primary lymphoma of Meckel's cave mimicking trigeminal schwannoma: case report.

Authors:  K M Abdel Aziz; H R van Loveren
Journal:  Neurosurgery       Date:  1999-04       Impact factor: 4.654

3.  Outcome of adult patients with T-lymphoblastic lymphoma treated according to protocols for acute lymphoblastic leukemia.

Authors:  Dieter Hoelzer; Nicola Gökbuget; Werner Digel; Thomas Faak; Michael Kneba; Regina Reutzel; Joanna Romejko-Jarosinska; Jacek Zwolinski; Jan Walewski
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4.  A series of 146 peripheral non-neural sheath nerve tumors: 30-year experience at Louisiana State University Health Sciences Center.

Authors:  Daniel H Kim; Judith A Murovic; Robert L Tiel; Gregory Moes; David G Kline
Journal:  J Neurosurg       Date:  2005-02       Impact factor: 5.115

5.  Rosai-Dorfman disease isolated to the central nervous system: a report of 11 cases.

Authors:  J A Andriko; A Morrison; C H Colegial; B J Davis; R V Jones
Journal:  Mod Pathol       Date:  2001-03       Impact factor: 7.842

6.  Prognostic factors in 140 adult patients with non-Hodgkin's lymphoma with systemic central nervous system (CNS) involvement. A single centre analysis.

Authors:  A Hollender; S Kvaloy; K Lote; O Nome; H Holte
Journal:  Eur J Cancer       Date:  2000-09       Impact factor: 9.162

7.  Malignant peripheral nerve sheath tumor of the spine after radiation therapy for Hodgkin's lymphoma.

Authors:  D C Adamson; T J Cummings; A H Friedman
Journal:  Clin Neuropathol       Date:  2004 Sep-Oct       Impact factor: 1.368

8.  Acute cauda equina compression revealing Hodgkin's disease: a case report.

Authors:  Laurent Riffaud; Mahmoudreza Adn; Gilles Brassier; Xavier Morandi
Journal:  Spine (Phila Pa 1976)       Date:  2003-07-15       Impact factor: 3.468

9.  Clinical, biologic, and histologic features of late relapses in diffuse large cell lymphoma.

Authors:  F Cabanillas; W S Velasquez; F B Hagemeister; P McLaughlin; J R Redman
Journal:  Blood       Date:  1992-02-15       Impact factor: 22.113

Review 10.  Lymphoma and peripheral neuropathy: a clinical review.

Authors:  John J Kelly; Donald S Karcher
Journal:  Muscle Nerve       Date:  2005-03       Impact factor: 3.217

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