Literature DB >> 18810491

Inhibition of HBV infection by bovine lactoferrin and iron-, zinc-saturated lactoferrin.

Songtao Li1, Haibo Zhou, Guirong Huang, Ning Liu.   

Abstract

In this study, we investigated the effect of bovine lactoferrin (BLf), lactoferrin hydrolysate, or iron-, zinc-saturated lactoferrin on hepatitis B virus (HBV)-infected HepG2 cells. Fluorescent quantitative polymerase chain reaction (FQ-PCR) was used to quantify HBV-DNA copies. BLf, iron- or zinc-saturated lactoferrin significantly inhibited the amplification of HBV-DNA in a dose-dependent manner in HBV-infected HepG2 cells. However, the inhibitive effect of lactoferrin hydrolysate on HBV-DNA copies was insignificant. These findings suggest that BLf inhibits the function of HBV by integrated structure. In conclusion, BLf, iron- or zinc-saturated BLf is one of the candidates for anti-HBV reagents in treatment of patients with hepatitis.

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Year:  2008        PMID： 18810491     DOI： 10.1007/s00430-008-0100-7

Source DB:  PubMed          Journal:  Med Microbiol Immunol        ISSN： 0300-8584            Impact factor:   3.402


  45 in total

1.  Genome of hepatitis B virus: restriction enzyme cleavage and structure of DNA extracted from Dane particles.

Authors:  J Summers; A O'Connell; I Millman
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2.  Nucleotide sequence of human lactoferrin cDNA.

Authors:  M J Powell; J E Ogden
Journal:  Nucleic Acids Res       Date:  1990-07-11       Impact factor: 16.971

3.  Antiviral effects of milk proteins: acylation results in polyanionic compounds with potent activity against human immunodeficiency virus types 1 and 2 in vitro.

Authors:  P J Swart; M E Kuipers; C Smit; R Pauwels; M P deBéthune; E de Clercq; D K Meijer; J G Huisman
Journal:  AIDS Res Hum Retroviruses       Date:  1996-06-10       Impact factor: 2.205

Review 4.  Hepatitis B virus infection.

Authors:  W M Lee
Journal:  N Engl J Med       Date:  1997-12-11       Impact factor: 91.245

Review 5.  The genome of hepatitis B virus.

Authors:  W S Robinson
Journal:  Annu Rev Microbiol       Date:  1977       Impact factor: 15.500

6.  Plasma lactoferrin levels are decreased in end-stage AIDS patients.

Authors:  B W van der Strate; M C Harmsen; T H The; H G Sprenger; H de Vries; M C Eikelboom; M E Kuipers; D K Meijer; P J Swart
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Review 7.  Lactoferrin and the inflammatory response.

Authors:  R D Baynes; W R Bezwoda
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9.  Iron transport across Caco-2 cell monolayers. Effect of transferrin, lactoferrin and nitric oxide.

Authors:  L Sánchez; M Ismail; F Y Liew; J H Brock
Journal:  Biochim Biophys Acta       Date:  1996-03-15

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Authors:  Y Inouye; T Kanamori; T Yoshida; X Bu; M Shionoya; T Koike; E Kimura
Journal:  Biol Pharm Bull       Date:  1994-02       Impact factor: 2.233
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  13 in total

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Review 10.  Immune-Boosting, Antioxidant and Anti-inflammatory Food Supplements Targeting Pathogenesis of COVID-19.

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