Literature DB >> 18809985

5-Oxoproline as a cause of high anion gap metabolic acidosis: an uncommon cause with common risk factors.

W Kortmann1, M A van Agtmael, J van Diessen, B L J Kanen, C Jakobs, P W B Nanayakkara.   

Abstract

High anion gap metabolic acidosis might be caused by 5-oxoproline (pyroglutamic acid). As it is very easy to treat, it might be worth drawing attention to this uncommon and probably often overlooked diagnosis. We present three cases of high anion gap metabolic acidosis due to 5-oxoproline seen within a period of six months.

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Year:  2008        PMID： 18809985

Source DB:  PubMed          Journal:  Neth J Med        ISSN： 0300-2977            Impact factor:   1.422


  12 in total

1.  5-Oxoprolinuria as a cause of high anion gap metabolic acidosis.

Authors:  Rajanshu Verma; Karthik R Polsani; Jeffrey Wilt; Mark E Loehrke
Journal:  Br J Clin Pharmacol       Date:  2012-03       Impact factor: 4.335

2.  Serum metabolomic profiles from patients with acute kidney injury: a pilot study.

Authors:  Jinchun Sun; Melissa Shannon; Yosuke Ando; Laura K Schnackenberg; Nasim A Khan; Didier Portilla; Richard D Beger
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2012-03-06       Impact factor: 3.205

3.  High anion gap metabolic acidosis: use the proper acronym, discard the red herrings and thou shall find the culprit.

Authors:  Willem Schurmans; Wim Lemahieu; Eric Frans
Journal:  Clin Kidney J       Date:  2014-05-14

Review 4.  Pharmacologically-induced metabolic acidosis: a review.

Authors:  George Liamis; Haralampos J Milionis; Moses Elisaf
Journal:  Drug Saf       Date:  2010-05-01       Impact factor: 5.606

5.  Refractory metabolic acidosis in patients with sepsis following hemiarthroplasty for femoral neck fracture: a causative role for paracetamol and flucloxacillin?

Authors:  Halima Amer; Frances Dockery; Nicholas Barrett; Marc George; Karolina Witek; Jeremy Stanton; Diane Back
Journal:  BMJ Case Rep       Date:  2011-07-20

Review 6.  Acetaminophen toxicity and 5-oxoproline (pyroglutamic acid): a tale of two cycles, one an ATP-depleting futile cycle and the other a useful cycle.

Authors:  Michael Emmett
Journal:  Clin J Am Soc Nephrol       Date:  2013-11-14       Impact factor: 8.237

7.  Serum metabolomic profiling and incident CKD among African Americans.

Authors:  Bing Yu; Yan Zheng; Jennifer A Nettleton; Danny Alexander; Josef Coresh; Eric Boerwinkle
Journal:  Clin J Am Soc Nephrol       Date:  2014-07-10       Impact factor: 8.237

8.  A not so simple analgesic.

Authors:  Sarah Howie; Anne Tarn; Charles Soper
Journal:  NDT Plus       Date:  2010-09-08

9.  Acetaminophen-induced anion gap metabolic acidosis secondary to 5-oxoproline: a case report.

Authors:  Tarig Mohammed Abkur; Waleed Mohammed; Mohamed Ali; Liam Casserly
Journal:  J Med Case Rep       Date:  2014-12-06

10.  Metabolic acidosis caused by concomitant use of paracetamol (acetaminophen) and flucloxacillin? A case report and a retrospective study.

Authors:  J K Berbee; L A Lammers; C T P Krediet; J C Fischer; E M Kemper
Journal:  Eur J Clin Pharmacol       Date:  2017-08-07       Impact factor: 2.953
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