Literature DB >> 18809984

Guilty as charged: unmeasured urinary anions in a case of pyroglutamic acidosis.

E J Rolleman1, E J Hoorn, P Didden, R Zietse.   

Abstract

A patient developed an unexplained metabolic acidosis with the characteristics of renal tubular acidosis. By correcting the serum anion gap for hypoalbuminaemia and analysing the urinary anions and cations, the presence of unmeasured anions was revealed. The diagnosis of pyroglutamic acidosis, caused by a combination of flucloxacillin and acetaminophen, was established. Strategies for solving complex cases of metabolic acidosis are discussed.

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Year:  2008        PMID： 18809984

Source DB:  PubMed          Journal:  Neth J Med        ISSN： 0300-2977            Impact factor:   1.422


  10 in total

1.  5-Oxoprolinuria as a cause of high anion gap metabolic acidosis.

Authors:  Rajanshu Verma; Karthik R Polsani; Jeffrey Wilt; Mark E Loehrke
Journal:  Br J Clin Pharmacol       Date:  2012-03       Impact factor: 4.335

2.  5-Oxoproline (pyroglutamic) acidosis associated with chronic acetaminophen use.

Authors:  Jennifer L Duewall; Andrew Z Fenves; Daniel S Richey; Long D Tran; Michael Emmett
Journal:  Proc (Bayl Univ Med Cent)       Date:  2010-01

3.  Serum metabolomic profiles from patients with acute kidney injury: a pilot study.

Authors:  Jinchun Sun; Melissa Shannon; Yosuke Ando; Laura K Schnackenberg; Nasim A Khan; Didier Portilla; Richard D Beger
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2012-03-06       Impact factor: 3.205

4.  Refractory metabolic acidosis in patients with sepsis following hemiarthroplasty for femoral neck fracture: a causative role for paracetamol and flucloxacillin?

Authors:  Halima Amer; Frances Dockery; Nicholas Barrett; Marc George; Karolina Witek; Jeremy Stanton; Diane Back
Journal:  BMJ Case Rep       Date:  2011-07-20

Review 5.  Drug-induced acid-base disorders.

Authors:  Daniel Kitterer; Matthias Schwab; M Dominik Alscher; Niko Braun; Joerg Latus
Journal:  Pediatr Nephrol       Date:  2014-11-05       Impact factor: 3.714

6.  Understanding lactic acidosis in paracetamol (acetaminophen) poisoning.

Authors:  Anoop D Shah; David M Wood; Paul I Dargan
Journal:  Br J Clin Pharmacol       Date:  2011-01       Impact factor: 4.335

Review 7.  Acetaminophen toxicity and 5-oxoproline (pyroglutamic acid): a tale of two cycles, one an ATP-depleting futile cycle and the other a useful cycle.

Authors:  Michael Emmett
Journal:  Clin J Am Soc Nephrol       Date:  2013-11-14       Impact factor: 8.237

Review 8.  Fluid, electrolyte and acid-base disorders associated with antibiotic therapy.

Authors:  R Zietse; R Zoutendijk; E J Hoorn
Journal:  Nat Rev Nephrol       Date:  2009-04       Impact factor: 28.314

9.  Transient 5-oxoprolinuria: unusually high anion gap acidosis in an infant.

Authors:  Sarah L Hulley; Jeff Perring; Nigel Manning; Simon Olpin; Sufin Yap
Journal:  Eur J Pediatr       Date:  2015-07-01       Impact factor: 3.183

10.  Metabolic acidosis caused by concomitant use of paracetamol (acetaminophen) and flucloxacillin? A case report and a retrospective study.

Authors:  J K Berbee; L A Lammers; C T P Krediet; J C Fischer; E M Kemper
Journal:  Eur J Clin Pharmacol       Date:  2017-08-07       Impact factor: 2.953
  10 in total

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