Literature DB >> 18809338

From the diet to the nucleus: vitamin A and TGF-beta join efforts at the mucosal interface of the intestine.

Daniel Mucida1, Yunji Park, Hilde Cheroutre.   

Abstract

The vitamin A metabolites, including retinoic acid (RA), form ligands for retinoic acid-related nuclear receptors and together they play pleiotropic roles in various biological processes. Recently, we described that RA also functions as a key modulator of transforming growth factor-beta (TGF-beta)-driven immune deviation, capable of suppressing the differentiation of interleukin-17 secreting T helper cells (T(H)17) and conversely promoting the generation of Foxp3(+) T regulatory (Treg) cells. This review will focus on the role of RA in the reciprocal TGF-beta-driven differentiation of T(H)17 and Treg and on the importance of such regulatory mechanism to control a functional immune system, in particular at the mucosal interface of the intestine.

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Year:  2008        PMID： 18809338      PMCID： PMC2643336          DOI： 10.1016/j.smim.2008.08.001

Source DB:  PubMed          Journal:  Semin Immunol        ISSN： 1044-5323            Impact factor:   11.130


  81 in total

1.  CC chemokine receptor 9 expression defines a subset of peripheral blood lymphocytes with mucosal T cell phenotype and Th1 or T-regulatory 1 cytokine profile.

Authors:  Konstantinos A Papadakis; Carol Landers; John Prehn; Elias A Kouroumalis; Sofia T Moreno; Jose-Carlos Gutierrez-Ramos; Martin R Hodge; Stephan R Targan
Journal:  J Immunol       Date:  2003-07-01       Impact factor: 5.422

2.  Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells.

Authors:  Estelle Bettelli; Yijun Carrier; Wenda Gao; Thomas Korn; Terry B Strom; Mohamed Oukka; Howard L Weiner; Vijay K Kuchroo
Journal:  Nature       Date:  2006-04-30       Impact factor: 49.962

3.  CCR7 is critically important for migration of dendritic cells in intestinal lamina propria to mesenteric lymph nodes.

Authors:  Myoung Ho Jang; Nagako Sougawa; Toshiyuki Tanaka; Takako Hirata; Takachika Hiroi; Kazuo Tohya; Zijin Guo; Eiji Umemoto; Yukihiko Ebisuno; Bo-Gie Yang; Ju-Young Seoh; Martin Lipp; Hiroshi Kiyono; Masayuki Miyasaka
Journal:  J Immunol       Date:  2006-01-15       Impact factor: 5.422

4.  Transforming growth factor-beta induces development of the T(H)17 lineage.

Authors:  Paul R Mangan; Laurie E Harrington; Darrell B O'Quinn; Whitney S Helms; Daniel C Bullard; Charles O Elson; Robin D Hatton; Sharon M Wahl; Trenton R Schoeb; Casey T Weaver
Journal:  Nature       Date:  2006-04-30       Impact factor: 49.962

5.  Foxp3 programs the development and function of CD4+CD25+ regulatory T cells.

Authors:  Jason D Fontenot; Marc A Gavin; Alexander Y Rudensky
Journal:  Nat Immunol       Date:  2003-03-03       Impact factor: 25.606

6.  Groucho/transducin-like Enhancer-of-split (TLE)-dependent and -independent transcriptional regulation by Runx3.

Authors:  Merav Yarmus; Eilon Woolf; Yael Bernstein; Ofer Fainaru; Varda Negreanu; Ditsa Levanon; Yoram Groner
Journal:  Proc Natl Acad Sci U S A       Date:  2006-05-01       Impact factor: 11.205

7.  Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10.

Authors:  C Bogdan; J Paik; Y Vodovotz; C Nathan
Journal:  J Biol Chem       Date:  1992-11-15       Impact factor: 5.157

Review 8.  Transforming growth factor-beta regulation of immune responses.

Authors:  Ming O Li; Yisong Y Wan; Shomyseh Sanjabi; Anna-Karin L Robertson; Richard A Flavell
Journal:  Annu Rev Immunol       Date:  2006       Impact factor: 28.527

9.  TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells.

Authors:  Marc Veldhoen; Richard J Hocking; Christopher J Atkins; Richard M Locksley; Brigitta Stockinger
Journal:  Immunity       Date:  2006-02       Impact factor: 31.745

10.  Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells.

Authors:  Tim Worbs; Ulrike Bode; Sheng Yan; Matthias W Hoffmann; Gabriele Hintzen; Günter Bernhardt; Reinhold Förster; Oliver Pabst
Journal:  J Exp Med       Date:  2006-03-13       Impact factor: 14.307
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  32 in total

1.  Mechanisms of immune tolerance relevant to food allergy.

Authors:  Brian P Vickery; Amy M Scurlock; Stacie M Jones; A Wesley Burks
Journal:  J Allergy Clin Immunol       Date:  2011-01-31       Impact factor: 10.793

2.  Which species are in your feces?

Authors:  Colby Zaph
Journal:  J Clin Invest       Date:  2010-11-22       Impact factor: 14.808

Review 3.  Molecular Mechanisms of the Action of Vitamin A in Th17/Treg Axis in Multiple Sclerosis.

Authors:  Mina Abdolahi; Parvaneh Yavari; Niyaz Mohammadzadeh Honarvar; Sama Bitarafan; Maryam Mahmoudi; Ali Akbar Saboor-Yaraghi
Journal:  J Mol Neurosci       Date:  2015-08-30       Impact factor: 3.444

Review 4.  Regulating the mucosal immune system: the contrasting roles of LIGHT, HVEM, and their various partners.

Authors:  Marcos W Steinberg; Jr-Wen Shui; Carl F Ware; Mitchell Kronenberg
Journal:  Semin Immunopathol       Date:  2009-06-03       Impact factor: 9.623

Review 5.  The Th17 pathway and inflammatory diseases of the intestines, lungs, and skin.

Authors:  Casey T Weaver; Charles O Elson; Lynette A Fouser; Jay K Kolls
Journal:  Annu Rev Pathol       Date:  2012-11-15       Impact factor: 23.472

Review 6.  Dendritic cell control of tolerogenic responses.

Authors:  Santhakumar Manicassamy; Bali Pulendran
Journal:  Immunol Rev       Date:  2011-05       Impact factor: 12.988

7.  Commensal Propionibacterium strain UF1 mitigates intestinal inflammation via Th17 cell regulation.

Authors:  Natacha Colliou; Yong Ge; Bikash Sahay; Minghao Gong; Mojgan Zadeh; Jennifer L Owen; Josef Neu; William G Farmerie; Francis Alonzo; Ken Liu; Dean P Jones; Shuzhao Li; Mansour Mohamadzadeh
Journal:  J Clin Invest       Date:  2017-09-25       Impact factor: 14.808

Review 8.  Vitamin A and retinoic acid in T cell-related immunity.

Authors:  A Catharine Ross
Journal:  Am J Clin Nutr       Date:  2012-10-10       Impact factor: 7.045

9.  Lower levels of vitamin A are associated with increased gastrointestinal graft-versus-host disease in children.

Authors:  Dana T Lounder; Pooja Khandelwal; Christopher E Dandoy; Sonata Jodele; Michael S Grimley; Gregory Wallace; Adam Lane; Cynthia Taggart; Ashley C Teusink-Cross; Kelly E Lake; Stella M Davies
Journal:  Blood       Date:  2017-03-09       Impact factor: 22.113

10.  Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets.

Authors:  Petronela Ancuta; Kuang-Yu Liu; Vikas Misra; Vanessa Sue Wacleche; Annie Gosselin; Xiaobo Zhou; Dana Gabuzda
Journal:  BMC Genomics       Date:  2009-08-27       Impact factor: 3.969
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