Determination of unbiased selectivity coefficients using pulsed chronopotentiometric polymeric membrane ion sensors.

A new procedure for the determination of selectivity coefficients of neutral carriers using pulsed chronopotentiometric ion selective sensors (pulstrodes) is established. Pulstrode membrane which lacks an ion-exchanger suppresses the zero current ion flux, allowing a Nernstian response slope for even highly discriminated ions. Unlike previously developed methods, unbiased selectivity remains unaltered even with the exposure to the primary ion solution for prolonged time. Studies with potassium-, silver-, and calcium-selective electrodes reveal that pulstrodes yield the same or slightly favorable unbiased selectivity coefficients than reported earlier. In contrast to alternative methods for the determination of unbiased selectivity, this technique offers a unique simplicity and reliability. Therefore the new procedure promises to be a valuable additional tool for the characterization of unbiased selectivity coefficients for the ISEs.