| Literature DB >> 18808131 |
José M Concellón1, Humberto Rodríguez-Solla, Carmen Simal, David Santos, Nieves R Paz.
Abstract
A method to obtain (Z)-beta,gamma-unsaturated nitriles in high or good yields and with moderate or high stereoselectivity is described. The products were achieved through the photoinduced metalation of 3-acetoxy-4-chloronitriles with SmI2. The starting compounds were readily prepared, and a mechanism is proposed to explain this stereoselective beta-elimination reaction.Entities:
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Year: 2008 PMID： 18808131 DOI： 10.1021/ol801752m
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005