Literature DB >> 18808128

Studies on the synthesis of durhamycin A: stereoselective synthesis of a model aglycone.

Rajan Pragani1, William R Roush.   

Abstract

A stereoselective synthesis of the model aglycone corresponding to the anti-HIV aureolic acids durhamycins A (1) and B (2) is described.

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Year:  2008        PMID： 18808128      PMCID： PMC2626543          DOI： 10.1021/ol8018727

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  22 in total

1.  UCH9, a new antitumor antibiotic produced by Streptomyces: I. Producing organism, fermentation, isolation and biological activities.

Authors:  H Ogawa; Y Yamashita; R Katahira; S Chiba; T Iwasaki; T Ashizawa; H Nakano
Journal:  J Antibiot (Tokyo)       Date:  1998-03       Impact factor: 2.649

Review 2.  The aureolic acid family of antitumor compounds: structure, mode of action, biosynthesis, and novel derivatives.

Authors:  Felipe Lombó; Nuria Menéndez; José A Salas; Carmen Méndez
Journal:  Appl Microbiol Biotechnol       Date:  2006-09-30       Impact factor: 4.813

3.  Pd/P(t-Bu)(3): a mild and general catalyst for Stille reactions of aryl chlorides and aryl bromides.

Authors:  Adam F Littke; Lothar Schwarz; Gregory C Fu
Journal:  J Am Chem Soc       Date:  2002-06-05       Impact factor: 15.419

4.  Solution structure of the novel antitumor drug UCH9 complexed with d(TTGGCCAA)2 as determined by NMR.

Authors:  R Katahira; M Katahira; Y Yamashita; H Ogawa; Y Kyogoku; M Yoshida
Journal:  Nucleic Acids Res       Date:  1998-02-01       Impact factor: 16.971

5.  Inhibition of c-src transcription by mithramycin: structure-activity relationships of biosynthetically produced mithramycin analogues using the c-src promoter as target.

Authors:  Lily L Remsing; Hamid R Bahadori; Giuseppina M Carbone; Eileen M McGuffie; Carlo V Catapano; Jürgen Rohr
Journal:  Biochemistry       Date:  2003-07-15       Impact factor: 3.162

6.  Solution structure of the mithramycin dimer-DNA complex.

Authors:  M Sastry; D J Patel
Journal:  Biochemistry       Date:  1993-07-06       Impact factor: 3.162

7.  Structure refinement of the chromomycin dimer-DNA oligomer complex in solution.

Authors:  X L Gao; P Mirau; D J Patel
Journal:  J Mol Biol       Date:  1992-01-05       Impact factor: 5.469

8.  (+)-saxitoxin: a first and second generation stereoselective synthesis.

Authors:  James J Fleming; Matthew D McReynolds; J Du Bois
Journal:  J Am Chem Soc       Date:  2007-07-21       Impact factor: 15.419

9.  Mithramycin analogues generated by combinatorial biosynthesis show improved bioactivity.

Authors:  Irfan Baig; María Perez; Alfredo F Braña; Rohini Gomathinayagam; Chendil Damodaran; Jose A Salas; Carmen Méndez; Jürgen Rohr
Journal:  J Nat Prod       Date:  2008-01-15       Impact factor: 4.050

10.  Durhamycin A, a potent inhibitor of HIV Tat transactivation.

Authors:  Hiranthi Jayasuriya; Russell B Lingham; Pia Graham; Donette Quamina; Lucia Herranz; Olga Genilloud; Magda Gagliardi; Renee Danzeisen; Joanne E Tomassini; Deborah L Zink; Ziqiang Guan; Sheo B Singh
Journal:  J Nat Prod       Date:  2002-08       Impact factor: 4.050
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  2 in total

1.  Stereoselective synthesis of gamma-substituted (Z)-allylic boranes via kinetically controlled hydroboration of allenes with 10-TMS-9-borabicyclo[3.3.2]decane.

Authors:  Jeremy Kister; Amy C DeBaillie; Ricardo Lira; William R Roush
Journal:  J Am Chem Soc       Date:  2009-10-14       Impact factor: 15.419

Review 2.  Role of Tat protein in HIV neuropathogenesis.

Authors:  Wenxue Li; Guanhan Li; Joseph Steiner; Avindra Nath
Journal:  Neurotox Res       Date:  2009-03-21       Impact factor: 3.911
  2 in total

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