Literature DB >> 188060

6-Hydroxydopamine and the aggressive behavior induced by marihuana in REM sleep-deprived rats.

R E Musty, C J Lindsey, E A Carlini.   

Abstract

6-Hydroxydopamine (6OH-DA) pretreatment increased the aggressive behavior induced by marihuana in REM sleep-deprived rats. Brain catecholamine assays revealed that 6OH-DA depleted popamine (DA) and norepinephrine (NE) to a different extent, increasing the DA/NE ratio. Intraventricular injection of NE significantly decreased the aggressive behavior of these animals, whereas control solution or DA injections had no effect. The possible role played by DA and NE in the aggressive behavior induced by marihuana in REM sleep-deprived rats is discussed.

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Year:  1976        PMID： 188060     DOI： 10.1007/bf00423257

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  24 in total

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5.  Aggressive behaviour elicited in rats by Cannabis sativa: effects of p-chlorophenylalanine and DOPA.

Authors:  J Palermo Neto; E A Carlini
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6.  The aggressive monoamines.

Authors:  B S Eichelman; N B Thoa
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7.  Shock-induced aggression: opposite effects of intraventricularly infused dopamine and norepinephrine.

Authors:  M A Geyer; D S Segal
Journal:  Behav Biol       Date:  1974-01

8.  Shock-induced aggression: effects of 6-hydroxydopamine and other pharmacological agents.

Authors:  N B Thoa; B Eichelman; L K Ng
Journal:  Brain Res       Date:  1972-08-25       Impact factor: 3.252

9.  The mechanism of action of psychopharmacological agents on behaviour.

Authors:  I Munkvad
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1975

10.  Spontaneous behavior and sleep-wakefulness cycle in isolated and paired REM sleep deprived-marihuana treated rats.

Authors:  J M Monti; E A Carlini
Journal:  Pharmacol Biochem Behav       Date:  1975 Nov-Dec       Impact factor: 3.533
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  3 in total

1.  Cannabis, catecholamines, rapid eye movement sleep and aggressive behaviour.

Authors:  E A Carlini; C J Lindsey; S Tufik
Journal:  Br J Pharmacol       Date:  1977-11       Impact factor: 8.739

2.  Screening hallucinogenic drugs II. Systematic study of two behavioral tests.

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Journal:  Psychopharmacology (Berl)       Date:  1978-01-31       Impact factor: 4.530

3.  Methyleugenol as a surgical anesthetic in rodents.

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  3 in total

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