Literature DB >> 18805665

Assessment of liver phagocytic activity using EPR spectrometry and imaging.

Nicolas Charlier1, Audrey M Neyrinck, Nelson Beghein, Nathalie M Delzenne, Bernard Gallez.   

Abstract

The aim of the present study was to evaluate the usefulness of electron paramagnetic resonance (EPR) spectroscopy and imaging in assessing the phagocytic activity of the liver after administration of India ink. We conducted experiments on livers from control rodents and from rodents in which the Kupffer cell population had been depleted by pretreatment with gadolinium chloride. The EPR signal intensity recorded in liver homogenates was about two times lower in GdCl(3) treated rats than in control rats. EPR imaging carried out on precision-cut liver slices indicated a good correlation between the depletion of Kupffer cells and the EPR signal intensity.

Entities:  

Mesh：

Year:  2008        PMID： 18805665     DOI： 10.1016/j.mri.2008.07.022

Source DB:  PubMed          Journal:  Magn Reson Imaging        ISSN： 0730-725X            Impact factor:   2.546


  3 in total

1.  Increased serum enzyme levels associated with kupffer cell reduction with no signs of hepatic or skeletal muscle injury.

Authors:  Zaher A Radi; Petra H Koza-Taylor; Rosonald R Bell; Leslie A Obert; Herbert A Runnels; Jean S Beebe; Michael P Lawton; Seth Sadis
Journal:  Am J Pathol       Date:  2011-05-13       Impact factor: 4.307

2.  Evaluation of the uptake function of liver in rats with obstructive jaundice before and after relief from obstruction by superparamagnetic iron oxide-enhanced magnetic resonance imaging.

Authors:  Zhou Yiming; Jiang Lei; Zhai Renyou; Ke Shan; Li Xue; Liu Min; Gao Jun
Journal:  Oncol Lett       Date:  2012-05-24       Impact factor: 2.967

Review 3.  Best Practices and Progress in Precision-Cut Liver Slice Cultures.

Authors:  Liza Dewyse; Hendrik Reynaert; Leo A van Grunsven
Journal:  Int J Mol Sci       Date:  2021-07-01       Impact factor: 5.923
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.