Literature DB >> 18805080

The discovery of statins.

Thomas P Stossel1.   

Abstract

This year, the Lasker Foundation confers its Clinical Medical Research Award on Akira Endo for his isolation from fungi of statins, potent inhibitors of cholesterol synthesis in the liver. The introduction of statins to clinical practice has markedly reduced morbidity and mortality from atherosclerotic cardiovascular disease.

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Year:  2008        PMID： 18805080     DOI： 10.1016/j.cell.2008.09.008

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  17 in total

Review 1.  Lipid control in patients with diabetes mellitus.

Authors:  D John Betteridge
Journal:  Nat Rev Cardiol       Date:  2011-03-15       Impact factor: 32.419

Review 2.  Genomic Medicine-Progress, Pitfalls, and Promise.

Authors:  Jay Shendure; Gregory M Findlay; Matthew W Snyder
Journal:  Cell       Date:  2019-03-21       Impact factor: 41.582

Review 3.  Systems pharmacology, pharmacogenetics, and clinical trial design in network medicine.

Authors:  Elliott Antman; Scott Weiss; Joseph Loscalzo
Journal:  Wiley Interdiscip Rev Syst Biol Med       Date:  2012-05-11

4.  New Approach For Simvastatin As An Antibacterial: Synergistic Effect With Bio-Synthesized Silver Nanoparticles Against Multidrug-Resistant Bacteria.

Authors:  E P Figueiredo; J M Ribeiro; E K Nishio; S Scandorieiro; A F Costa; V F Cardozo; A G Oliveira; N Durán; L A Panagio; Rkt Kobayashi; G Nakazato
Journal:  Int J Nanomedicine       Date:  2019-10-03

5.  The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase.

Authors:  Marc M Schumacher; Rania Elsabrouty; Joachim Seemann; Youngah Jo; Russell A DeBose-Boyd
Journal:  Elife       Date:  2015-03-05       Impact factor: 8.140

Review 6.  Efforts to make and apply humanized yeast.

Authors:  Jon M Laurent; Jonathan H Young; Aashiq H Kachroo; Edward M Marcotte
Journal:  Brief Funct Genomics       Date:  2015-10-13       Impact factor: 4.241

Review 7.  Second-generation probes for biosynthetic intermediate capture: towards a comprehensive profiling of polyketide assembly.

Authors:  Ina Wilkening; Silvia Gazzola; Elena Riva; James S Parascandolo; Lijiang Song; Manuela Tosin
Journal:  Chem Commun (Camb)       Date:  2016-08-16       Impact factor: 6.222

8.  Schnyder corneal dystrophy-associated UBIAD1 inhibits ER-associated degradation of HMG CoA reductase in mice.

Authors:  Youngah Jo; Jason S Hamilton; Seonghwan Hwang; Kristina Garland; Gennipher A Smith; Shan Su; Iris Fuentes; Sudha Neelam; Bonne M Thompson; Jeffrey G McDonald; Russell A DeBose-Boyd
Journal:  Elife       Date:  2019-02-20       Impact factor: 8.140

Review 9.  Statin as a Potential Chemotherapeutic Agent: Current Updates as a Monotherapy, Combination Therapy, and Treatment for Anti-Cancer Drug Resistance.

Authors:  Nirmala Tilija Pun; Chul-Ho Jeong
Journal:  Pharmaceuticals (Basel)       Date:  2021-05-16

Review 10.  Exploitation of Aspergillus terreus for the Production of Natural Statins.

Authors:  Mishal Subhan; Rani Faryal; Ian Macreadie
Journal:  J Fungi (Basel)       Date:  2016-04-30
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