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Literature DB >> 18804825

Cytotoxic and antiplasmodial substances from marine-derived fungi, Nodulisporium sp. and CRI247-01.

Chairut Kasettrathat¹, Nattaya Ngamrojanavanich, Suthep Wiyakrutta, Chulabhorn Mahidol, Somsak Ruchirawat, Prasat Kittakoop.

Abstract

Nodulisporacid A (1) was isolated from a marine-derived fungus Nodulisporium sp. CRIF1, while vermelhotin (5) was obtained from an unidentified fungus CRI247-01 (a member of the Order Pleosporales). Both 1 and 5 occurred as equilibrium E/Z mixtures. Ester derivatives (2 and 3) and vermelhotin (5) showed cytotoxic activity against eleven cancer cell lines. Nodulisporacid A (1) and vermelhotin (5) exhibited moderate antiplasmodial activity.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2008 PMID： 18804825 DOI： 10.1016/j.phytochem.2008.08.005

Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072

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Cited

7 in total

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Authors: Katharine R Watts; Karen Tenney; Phillip Crews
Journal: Curr Opin Biotechnol Date: 2010-10-16 Impact factor: 9.740

2. Lindgomycin, an Unusual Antibiotic Polyketide from a Marine Fungus of the Lindgomycetaceae.

Authors: Bin Wu; Jutta Wiese; Antje Labes; Annemarie Kramer; Rolf Schmaljohann; Johannes F Imhoff
Journal: Mar Drugs Date: 2015-07-27 Impact factor: 5.118

Review 3. Bioactive Secondary Metabolites from Octocoral-Associated Microbes-New Chances for Blue Growth.

Authors: Inês Raimundo; Sandra G Silva; Rodrigo Costa; Tina Keller-Costa
Journal: Mar Drugs Date: 2018-12-04 Impact factor: 5.118

Review 4. Marine pharmacology in 2007-8: Marine compounds with antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, antituberculosis, and antiviral activities; affecting the immune and nervous system, and other miscellaneous mechanisms of action.

Authors: Alejandro M S Mayer; Abimael D Rodríguez; Roberto G S Berlinck; Nobuhiro Fusetani
Journal: Comp Biochem Physiol C Toxicol Pharmacol Date: 2010-09-15 Impact factor: 3.228

Cytotoxic and antiplasmodial substances from marine-derived fungi, Nodulisporium sp. and CRI247-01.

Review 1. The structural diversity and promise of antiparasitic marine invertebrate-derived small molecules.

2. Lindgomycin, an Unusual Antibiotic Polyketide from a Marine Fungus of the Lindgomycetaceae.

Review 3. Bioactive Secondary Metabolites from Octocoral-Associated Microbes-New Chances for Blue Growth.

Review 4. Marine pharmacology in 2007-8: Marine compounds with antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, antituberculosis, and antiviral activities; affecting the immune and nervous system, and other miscellaneous mechanisms of action.

Review 5. The Biological and Chemical Diversity of Tetramic Acid Compounds from Marine-Derived Microorganisms.

Review 6. Recent Updates on Marine Cancer-Preventive Compounds.

7. Unstable Tetramic Acid Derivatives from the Deep-Sea-Derived Fungus Cladosporium sphaerospermum EIODSF 008.