BACKGROUND: Geographical variation and sociodemographic characteristics may differ in affective and nonaffective psychotic disorders. We examined the geographical variation in the lifetime prevalence of psychotic disorders in a comprehensive general population study. METHOD: A nationally representative sample of 8028 Finns aged 30 or over was screened for psychotic and bipolar I disorders and interviewed with the Structured Clinical Interview for DSM-IV. Best-estimate DSM-IV diagnoses were formed by combining interview and case note data. Nationwide health care register data were used for the nonrespondents. Associations with sociodemographic features, place of birth and residence in urban or rural areas and in five regions, and migration between the regions were examined. RESULTS: Schizophrenia and other nonaffective psychoses, but not affective psychoses, showed prominent regional variation, with highest odds found for schizophrenia among those born in the North (OR 7.72 95%CI 2.48-24.04) and the East (OR 3.99 95%CI 1.22-13.11). The risk of any psychotic disorder was lower for those born in urban areas (OR 0.73 95%CI 0.54-0.98), but no associations were found for separate diagnostic groups. Region of birth was the strongest determinant of geographical variation when both place of birth and residence were accounted for. Selective migration was not found. Education and income were higher and being employed more common in subjects with affective psychosis than in subjects with other psychotic disorders. CONCLUSIONS: Large area variation is more important than urban-rural disparity in psychotic disorders in Finland. Affective psychoses were different from nonaffective psychoses in terms of both regional variation and sociodemographic features.
BACKGROUND: Geographical variation and sociodemographic characteristics may differ in affective and nonaffective psychotic disorders. We examined the geographical variation in the lifetime prevalence of psychotic disorders in a comprehensive general population study. METHOD: A nationally representative sample of 8028 Finns aged 30 or over was screened for psychotic and bipolar I disorders and interviewed with the Structured Clinical Interview for DSM-IV. Best-estimate DSM-IV diagnoses were formed by combining interview and case note data. Nationwide health care register data were used for the nonrespondents. Associations with sociodemographic features, place of birth and residence in urban or rural areas and in five regions, and migration between the regions were examined. RESULTS:Schizophrenia and other nonaffective psychoses, but not affective psychoses, showed prominent regional variation, with highest odds found for schizophrenia among those born in the North (OR 7.72 95%CI 2.48-24.04) and the East (OR 3.99 95%CI 1.22-13.11). The risk of any psychotic disorder was lower for those born in urban areas (OR 0.73 95%CI 0.54-0.98), but no associations were found for separate diagnostic groups. Region of birth was the strongest determinant of geographical variation when both place of birth and residence were accounted for. Selective migration was not found. Education and income were higher and being employed more common in subjects with affective psychosis than in subjects with other psychotic disorders. CONCLUSIONS: Large area variation is more important than urban-rural disparity in psychotic disorders in Finland. Affective psychoses were different from nonaffective psychoses in terms of both regional variation and sociodemographic features.
Authors: Alejandra Pinto-Meza; Maria Victoria Moneta; Jordi Alonso; Matthias C Angermeyer; Ronny Bruffaerts; José Miguel Caldas de Almeida; Giovanni de Girolamo; Ron de Graaf; Silvia Florescu; Viviane Kovess Masfety; Siobhan O'Neill; Svetlozar Vassilev; Josep Maria Haro Journal: Soc Psychiatry Psychiatr Epidemiol Date: 2012-07-18 Impact factor: 4.328
Authors: Sini Kerminen; Alicia R Martin; Jukka Koskela; Sanni E Ruotsalainen; Aki S Havulinna; Ida Surakka; Aarno Palotie; Markus Perola; Veikko Salomaa; Mark J Daly; Samuli Ripatti; Matti Pirinen Journal: Am J Hum Genet Date: 2019-05-30 Impact factor: 11.025
Authors: Jaana T Suokas; Jaana M Suvisaari; Jari Haukka; Pasi Korhonen; Jari Tiihonen Journal: Soc Psychiatry Psychiatr Epidemiol Date: 2012-09-25 Impact factor: 4.328
Authors: Georg Stoll; Olli P H Pietiläinen; Bastian Linder; Jaana Suvisaari; Cornelia Brosi; William Hennah; Virpi Leppä; Minna Torniainen; Samuli Ripatti; Sirpa Ala-Mello; Oliver Plöttner; Karola Rehnström; Annamari Tuulio-Henriksson; Teppo Varilo; Jonna Tallila; Kati Kristiansson; Matti Isohanni; Jaakko Kaprio; Johan G Eriksson; Olli T Raitakari; Terho Lehtimäki; Marjo-Riitta Jarvelin; Veikko Salomaa; Matthew Hurles; Hreinn Stefansson; Leena Peltonen; Patrick F Sullivan; Tiina Paunio; Jouko Lönnqvist; Mark J Daly; Utz Fischer; Nelson B Freimer; Aarno Palotie Journal: Nat Neurosci Date: 2013-08-04 Impact factor: 24.884
Authors: Marjaana A Peltola; Juha Kuja-Panula; Johanna Liuhanen; Vootele Võikar; Petteri Piepponen; Tero Hiekkalinna; Tomi Taira; Sari E Lauri; Jaana Suvisaari; Natalia Kulesskaya; Tiina Paunio; Heikki Rauvala Journal: Schizophr Bull Date: 2015-08-03 Impact factor: 9.306