Literature DB >> 18804231

Race and socioeconomic status are independently associated with benign prostatic hyperplasia.

Jay H Fowke1, Harvey J Murff, Lisa B Signorello, Lars Lund, William J Blot.   

Abstract

PURPOSE: Prostate enlargement is common as men age. However, differences in the diagnosis or treatment of clinical benign prostatic hyperplasia between black and white men remain poorly understood. We investigated racial differences in and surgical intervention for benign prostatic hyperplasia in a large and predominantly low income population.
MATERIALS AND METHODS: Participants included 21,949 men, of whom 79.8% were black and 20.2% were white, recruited from 60 community health centers in the southeastern United States between 2002 and 2007. Benign prostatic hyperplasia, surgical intervention for benign prostatic hyperplasia, and economic and demographic indexes, eg education, household income, health insurance and marital status, were determined by an interview in person. Logistic regression was used to summarize the association between race and benign prostatic hyperplasia while controlling for health care access and socioeconomic status.
RESULTS: Black men were approximately half as likely to report a benign prostatic hyperplasia diagnosis compared to white men (4.1% vs 9.9%, age adjusted OR 0.45, 95% CI 0.40, 0.51), a difference that persisted with only small abatement after controlling for age, income, insurance coverage, comorbidity, education and other factors (adjusted OR 0.49, 95% CI 0.43, 0.56)). Of men with benign prostatic hyperplasia surgical intervention for that condition (133 patients) was more prevalent in black vs white men (12.9% vs 9.1%, adjusted OR 1.65, 95% CI 1.10, 2.48).
CONCLUSIONS: After controlling for economic factors associated with benign prostatic hyperplasia black men were significantly less likely to report a prior benign prostatic hyperplasia diagnosis. In contrast, surgical intervention typically reserved for severe benign prostatic hyperplasia was more common in black men. Our results suggest that race and socioeconomic status are independently associated with benign prostatic hyperplasia.

Entities:  

Mesh:

Year:  2008        PMID: 18804231      PMCID: PMC2692430          DOI: 10.1016/j.juro.2008.07.059

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  17 in total

Review 1.  Racial differences in the androgen/androgen receptor pathway in prostate cancer.

Authors:  C A Pettaway
Journal:  J Natl Med Assoc       Date:  1999-12       Impact factor: 1.798

2.  Racial differences in cellular composition of benign prostatic hyperplasia.

Authors:  Y Aoki; Y Arai; H Maeda; K Okubo; K Shinohara
Journal:  Prostate       Date:  2001-12-01       Impact factor: 4.104

3.  Prevalence of and racial/ethnic variation in lower urinary tract symptoms and noncancer prostate surgery in U.S. men.

Authors:  Elizabeth A Platz; Ellen Smit; Gary C Curhan; Leroy M Nyberg; Edward Giovannucci
Journal:  Urology       Date:  2002-06       Impact factor: 2.649

4.  Serum androgen concentrations in young men: a longitudinal analysis of associations with age, obesity, and race. The CARDIA male hormone study.

Authors:  Susan M Gapstur; Peter H Gann; Peter Kopp; Laura Colangelo; Christopher Longcope; Kiang Liu
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2002-10       Impact factor: 4.254

5.  Incidence of surgically treated benign prostatic hypertrophy and of prostate cancer among blacks and whites in a prepaid health care plan.

Authors:  S Sidney; C P Quesenberry; M C Sadler; H A Guess; E G Lydick; E V Cattolica
Journal:  Am J Epidemiol       Date:  1991-10-15       Impact factor: 4.897

Review 6.  The natural history of benign prostatic hyperplasia: what have we learned in the last decade?

Authors:  R S Kirby
Journal:  Urology       Date:  2000-11-01       Impact factor: 2.649

7.  Racial variation in CAG repeat lengths within the androgen receptor gene among prostate cancer patients of lower socioeconomic status.

Authors:  Charles L Bennett; Douglas K Price; Simon Kim; Dachao Liu; Borko D Jovanovic; Derek Nathan; Margaret E Johnson; Jeffrey S Montgomery; Kelly Cude; Justin C Brockbank; Oliver Sartor; William D Figg
Journal:  J Clin Oncol       Date:  2002-09-01       Impact factor: 44.544

8.  IGF-1 and IGFBP-3 gene variants influence on serum levels and prostate cancer risk in African-Americans.

Authors:  Wenndy Hernandez; Cassandra Grenade; Eunice R Santos; Carolina Bonilla; Chiledum Ahaghotu; Rick A Kittles
Journal:  Carcinogenesis       Date:  2007-08-27       Impact factor: 4.944

9.  Androgen concentration in blacks with benign and malignant prostatic disease.

Authors:  D N Osegbe; J O Ogunlewe
Journal:  J Urol       Date:  1988-07       Impact factor: 7.450

10.  Comparison of lower urinary tract symptom severity and associated bother between community-dwelling black and white men: the Olmsted County Study of Urinary Symptoms and Health Status and the Flint Men's Health Study.

Authors:  Aruna V Sarma; John T Wei; Debra J Jacobson; Rodney L Dunn; Rosebud O Roberts; Cynthia J Girman; Michael M Lieber; Kathleen A Cooney; David Schottenfeld; James E Montie; Steven J Jacobsen
Journal:  Urology       Date:  2003-06       Impact factor: 2.649

View more
  5 in total

1.  The Southern Community Cohort Study: investigating health disparities.

Authors:  Lisa B Signorello; Margaret K Hargreaves; William J Blot
Journal:  J Health Care Poor Underserved       Date:  2010-02

2.  Effects of strong CYP2D6 and 3A4 inhibitors, paroxetine and ketoconazole, on the pharmacokinetics and cardiovascular safety of tamsulosin.

Authors:  Joachim Troost; Shinji Tatami; Yasuhiro Tsuda; Michaela Mattheus; Ludwig Mehlburger; Martina Wein; Martin C Michel
Journal:  Br J Clin Pharmacol       Date:  2011-08       Impact factor: 4.335

3.  Association between socioeconomic status (SES) and lower urinary tract symptom (LUTS) severity among black and white men.

Authors:  Jay H Fowke; Heather Munro; Lisa B Signorello; William J Blot; David F Penson
Journal:  J Gen Intern Med       Date:  2011-07-01       Impact factor: 5.128

4.  Differential adoption of laser prostatectomy for treatment of benign prostatic hyperplasia.

Authors:  Florian R Schroeck; John M Hollingsworth; Brent K Hollenbeck; Bruce L Jacobs; Anne M Suskind; Aruna V Sarma; John T Wei
Journal:  Urology       Date:  2013-03-19       Impact factor: 2.649

5.  Transrectal Doppler Sonography of Benign Prostatic Enlargement in Nigerian Men.

Authors:  Olubukola Olayinka Fanimi; Christianah Mopelola Asaleye; Abdulkadir Ayo Salako; Oluwagbemiga Oluwole Ayoola; Tewogbade Adeoye Adedeji; Bukunmi Michael Idowu
Journal:  J Med Ultrasound       Date:  2019-05-13
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.