Literature DB >> 18802490

Biology of HIV mucosal transmission.

Li Wu1.   

Abstract

PURPOSE OF REVIEW: HIV-1 mucosal transmission plays a critical role in HIV-1 infection and AIDS pathogenesis. This review summarizes the latest advances in biological studies of HIV-1 mucosal transmission, highlighting the implications of these studies in the development of microbicides to prevent HIV-1 transmission. RECENT
FINDINGS: New studies of initial HIV-1 infection using improved culture models updated the current view of mucosal transmission. Mechanistic studies enhanced our understanding of cell-cell transmission of HIV-1 mediated by the major target cells, including dendritic cells, CD4(+) T cells, and macrophages. Increasing evidence indicated the significance of host factors and immune responses in HIV-1 mucosal infection and transmission.
SUMMARY: Recent progress in HIV-1 mucosal infection and transmission enriches our knowledge of virus-host interactions and viral pathogenesis. Functional studies of HIV-1 interactions with host cells can provide new insights into the design of more effective approaches to combat HIV-1 infection and AIDS.

Entities:  

Keywords:  HIV; biology; infection; mucosal; transmission

Year:  2008        PMID： 18802490      PMCID： PMC2542876          DOI： 10.1097/COH.0b013e32830634c6

Source DB:  PubMed          Journal:  Curr Opin HIV AIDS        ISSN： 1746-630X            Impact factor:   4.283


  76 in total

1.  Covert human immunodeficiency virus replication in dendritic cells and in DC-SIGN-expressing cells promotes long-term transmission to lymphocytes.

Authors:  Cinzia Nobile; Caroline Petit; Arnaud Moris; Katharina Skrabal; Jean-Pierre Abastado; Fabrizio Mammano; Olivier Schwartz
Journal:  J Virol       Date:  2005-05       Impact factor: 5.103

2.  Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection.

Authors:  Rebecca D Wiley; Suryaram Gummuluru
Journal:  Proc Natl Acad Sci U S A       Date:  2006-01-09       Impact factor: 11.205

3.  Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu.

Authors:  Stuart J D Neil; Trinity Zang; Paul D Bieniasz
Journal:  Nature       Date:  2008-01-16       Impact factor: 49.962

4.  CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms.

Authors:  Matthew J Dolan; Hemant Kulkarni; Jose F Camargo; Weijing He; Alison Smith; Juan-Manuel Anaya; Toshiyuki Miura; Frederick M Hecht; Manju Mamtani; Florencia Pereyra; Vincent Marconi; Andrea Mangano; Luisa Sen; Rosa Bologna; Robert A Clark; Stephanie A Anderson; Judith Delmar; Robert J O'Connell; Andrew Lloyd; Jeffrey Martin; Seema S Ahuja; Brian K Agan; Bruce D Walker; Steven G Deeks; Sunil K Ahuja
Journal:  Nat Immunol       Date:  2007-10-21       Impact factor: 25.606

5.  Productive infection of human immunodeficiency virus type 1 in dendritic cells requires fusion-mediated viral entry.

Authors:  Alicia M Janas; Chunsheng Dong; Jian-Hua Wang; Li Wu
Journal:  Virology       Date:  2008-03-10       Impact factor: 3.616

6.  Semen-derived amyloid fibrils drastically enhance HIV infection.

Authors:  Jan Münch; Elke Rücker; Ludger Ständker; Knut Adermann; Christine Goffinet; Michael Schindler; Steffen Wildum; Raghavan Chinnadurai; Devi Rajan; Anke Specht; Guillermo Giménez-Gallego; Pedro Cuevas Sánchez; Douglas M Fowler; Atanas Koulov; Jeffery W Kelly; Walther Mothes; Jean-Charles Grivel; Leonid Margolis; Oliver T Keppler; Wolf-Georg Forssmann; Frank Kirchhoff
Journal:  Cell       Date:  2007-12-14       Impact factor: 41.582

7.  Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication.

Authors:  Ashleigh Hodges; Katherine Sharrocks; Mariola Edelmann; Dilair Baban; Arnaud Moris; Olivier Schwartz; Hal Drakesmith; Kay Davies; Benedikt Kessler; Andrew McMichael; Alison Simmons
Journal:  Nat Immunol       Date:  2007-05-13       Impact factor: 25.606

8.  Differential susceptibility of naïve, central memory and effector memory T cells to dendritic cell-mediated HIV-1 transmission.

Authors:  Fedde Groot; Toni M M van Capel; Joost Schuitemaker; Ben Berkhout; Esther C de Jong
Journal:  Retrovirology       Date:  2006-08-17       Impact factor: 4.602

9.  In macrophages, HIV-1 assembles into an intracellular plasma membrane domain containing the tetraspanins CD81, CD9, and CD53.

Authors:  Magdalena Deneka; Annegret Pelchen-Matthews; Rahel Byland; Ezequiel Ruiz-Mateos; Mark Marsh
Journal:  J Cell Biol       Date:  2007-04-16       Impact factor: 10.539

10.  Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy.

Authors:  Pauline Chugh; Birgit Bradel-Tretheway; Carlos M R Monteiro-Filho; Vicente Planelles; Sanjay B Maggirwar; Stephen Dewhurst; Baek Kim
Journal:  Retrovirology       Date:  2008-01-31       Impact factor: 4.602
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  26 in total

1.  Macropinocytosis and cytoskeleton contribute to dendritic cell-mediated HIV-1 transmission to CD4+ T cells.

Authors:  Jian-Hua Wang; Clive Wells; Li Wu
Journal:  Virology       Date:  2008-09-18       Impact factor: 3.616

2.  Stimulation of HIV-1 replication in immature dendritic cells in contact with primary CD4 T or B lymphocytes.

Authors:  Vincent Holl; Ke Xu; Maryse Peressin; Alexandre Lederle; Marina Elizabeth Biedma; Maryse Delaporte; Thomas Decoville; Sylvie Schmidt; Géraldine Laumond; Anne-Marie Aubertin; Christiane Moog
Journal:  J Virol       Date:  2010-02-10       Impact factor: 5.103

3.  Effects of different routes of administration on the immunogenicity of the Tat protein and a Tat-derived peptide.

Authors:  Valentina Finessi; Francesco Nicoli; Eleonora Gallerani; Fabio Sforza; Mariaconcetta Sicurella; Aurelio Cafaro; Antonella Caputo; Barbara Ensoli; Riccardo Gavioli
Journal:  Hum Vaccin Immunother       Date:  2015       Impact factor: 3.452

4.  Recombinant expression, purification, and biophysical characterization of the transmembrane and membrane proximal domains of HIV-1 gp41.

Authors:  Zhen Gong; Sarah A Kessans; Lusheng Song; Katerina Dörner; Ho-Hsien Lee; Lydia R Meador; Joshua LaBaer; Brenda G Hogue; Tsafrir S Mor; Petra Fromme
Journal:  Protein Sci       Date:  2014-09-03       Impact factor: 6.725

5.  Distribution of immune cells in the human cervix and implications for HIV transmission.

Authors:  Radiana T Trifonova; Judy Lieberman; Debbie van Baarle
Journal:  Am J Reprod Immunol       Date:  2014-01-10       Impact factor: 3.886

6.  Intercellular adhesion molecule 1 (ICAM-1), but not ICAM-2 and -3, is important for dendritic cell-mediated human immunodeficiency virus type 1 transmission.

Authors:  Jian-Hua Wang; Constance Kwas; Li Wu
Journal:  J Virol       Date:  2009-02-11       Impact factor: 5.103

7.  Transcriptional restriction of human immunodeficiency virus type 1 gene expression in undifferentiated primary monocytes.

Authors:  Chunsheng Dong; Constance Kwas; Li Wu
Journal:  J Virol       Date:  2009-02-11       Impact factor: 5.103

8.  PPARgamma and LXR signaling inhibit dendritic cell-mediated HIV-1 capture and trans-infection.

Authors:  Timothy M Hanley; Wendy Blay Puryear; Suryaram Gummuluru; Gregory A Viglianti
Journal:  PLoS Pathog       Date:  2010-07-01       Impact factor: 6.823

Review 9.  Does HIV Exploit the Inflammatory Milieu of the Male Genital Tract for Successful Infection?

Authors:  Rachel T Esra; Abraham J Olivier; Jo-Ann S Passmore; Heather B Jaspan; Rushil Harryparsad; Clive M Gray
Journal:  Front Immunol       Date:  2016-06-24       Impact factor: 7.561

Review 10.  HIV interactions with monocytes and dendritic cells: viral latency and reservoirs.

Authors:  Christopher M Coleman; Li Wu
Journal:  Retrovirology       Date:  2009-06-01       Impact factor: 4.602
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