Literature DB >> 18800159

RAPping production of type I interferon in pDCs through mTOR.

Mauro Costa-Mattioli1, Nahum Sonenberg.   

Abstract

The production of type I interferon -- the first line of defense against virus infection and critical for innate immunity -- in plasmacytoid dendritic cells relies on the mammalian target of rapamycin.

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Year:  2008        PMID： 18800159     DOI： 10.1038/ni1008-1097

Source DB:  PubMed          Journal:  Nat Immunol        ISSN： 1529-2908            Impact factor:   25.606


  16 in total

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2.  Reduction of infection by inhibiting mTOR pathway is associated with reversed repression of type I interferon by porcine reproductive and respiratory syndrome virus.

Authors:  Qinfang Liu; Laura C Miller; Frank Blecha; Yongming Sang
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Review 3.  The PI3K Pathway in Human Disease.

Authors:  David A Fruman; Honyin Chiu; Benjamin D Hopkins; Shubha Bagrodia; Lewis C Cantley; Robert T Abraham
Journal:  Cell       Date:  2017-08-10       Impact factor: 41.582

4.  Rapamycin enhances the activity of oncolytic herpes simplex virus against tumor cells that are resistant to virus replication.

Authors:  Xinping Fu; Lihua Tao; Armando Rivera; Xiaoliu Zhang
Journal:  Int J Cancer       Date:  2011-02-26       Impact factor: 7.396

5.  Production of interferon α by human immunodeficiency virus type 1 in human plasmacytoid dendritic cells is dependent on induction of autophagy.

Authors:  Dejiang Zhou; Kyung Hee Kang; Stephen A Spector
Journal:  J Infect Dis       Date:  2012-03-06       Impact factor: 5.226

6.  The mucosal expression pattern of interferon-ε in rhesus macaques.

Authors:  Andrew Demers; Guobin Kang; Fungrui Ma; Wuxun Lu; Zhe Yuan; Yue Li; Mark Lewis; Edmundo N Kraiselburd; Luis Montaner; Qingsheng Li
Journal:  J Leukoc Biol       Date:  2014-08-19       Impact factor: 4.962

7.  Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type I IFN production.

Authors:  Tommy Alain; XueQing Lun; Yvan Martineau; Polen Sean; Bali Pulendran; Emmanuel Petroulakis; Franz J Zemp; Chantal G Lemay; Dominic Roy; John C Bell; George Thomas; Sara C Kozma; Peter A Forsyth; Mauro Costa-Mattioli; Nahum Sonenberg
Journal:  Proc Natl Acad Sci U S A       Date:  2010-01-04       Impact factor: 11.205

8.  The Protozoan Parasite Toxoplasma gondii Selectively Reprograms the Host Cell Translatome.

Authors:  Julie Lorent; Tyson E Graber; Louis-Philippe Leroux; Visnu Chaparro; Laia Masvidal; Maria Aguirre; Bruno D Fonseca; Léon C van Kempen; Tommy Alain; Ola Larsson; Maritza Jaramillo
Journal:  Infect Immun       Date:  2018-08-22       Impact factor: 3.441

9.  Inhibition of mTORC1 Enhances the Translation of Chikungunya Proteins via the Activation of the MnK/eIF4E Pathway.

Authors:  Pierre-Emmanuel Joubert; Kenneth Stapleford; Florence Guivel-Benhassine; Marco Vignuzzi; Olivier Schwartz; Matthew L Albert
Journal:  PLoS Pathog       Date:  2015-08-28       Impact factor: 6.823

Review 10.  From scourge to cure: tumour-selective viral pathogenesis as a new strategy against cancer.

Authors:  Carolina S Ilkow; Stephanie L Swift; John C Bell; Jean-Simon Diallo
Journal:  PLoS Pathog       Date:  2014-01-16       Impact factor: 6.823
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