Literature DB >> 18798101

Mechanisms of action of antithymocyte globulin: old dogs with new tricks!

Mohamad Mohty1, Beatrice Gaugler.   

Abstract

Understanding the mechanisms underlying immunological tolerance is the key to successful transplantation. Recent findings demonstrate that polyclonal antibodies such as the antithymocyte globulins preparations can provide wide spectrum immunomodulation, suggesting that their use in the immunosuppression therapeutic armamentarium may help in reducing the incidence of organ rejection and improving patients' outcome after hematopoietic stem cell transplantation.

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Year:  2008        PMID: 18798101     DOI: 10.1080/10428190802163321

Source DB:  PubMed          Journal:  Leuk Lymphoma        ISSN: 1026-8022


  9 in total

1.  Discrepancy in the kinetics of total and active anti-thymocyte globulin blood concentrations in recipients of allogeneic hematopoietic stem cell transplantation.

Authors:  Akiko Yamane; Takehiko Mori; Jun Kato; Yukako Ono; Shinichiro Okamoto
Journal:  Int J Hematol       Date:  2011-03-08       Impact factor: 2.490

2.  Induction of self-antigen-specific Foxp3+ regulatory T cells in the periphery by lymphodepletion treatment with anti-mouse thymocyte globulin in mice.

Authors:  Yan Lu; Jun Suzuki; Maria Guillioli; Oliver Umland; Zhibin Chen
Journal:  Immunology       Date:  2011-06-29       Impact factor: 7.397

Review 3.  Thymoglobulin--new approaches to optimal outcomes.

Authors:  Andreea Delia Moicean; Anca Maria Popp; Ioanel Sinescu
Journal:  J Med Life       Date:  2009 Jul-Sep

4.  Antithymocyte Globulin Induces a Tolerogenic Phenotype in Human Dendritic Cells.

Authors:  Tobias Roider; Michael Katzfuß; Carina Matos; Katrin Singer; Kathrin Renner; Peter J Oefner; Katja Dettmer-Wilde; Wolfgang Herr; Ernst Holler; Marina Kreutz; Katrin Peter
Journal:  Int J Mol Sci       Date:  2016-12-11       Impact factor: 5.923

5.  Conventional alpha beta (αβ) T cells do not contribute to acute intestinal ischemia-reperfusion injury in mice.

Authors:  Yi Yu; Xiaoyan Feng; Gertrud Vieten; Stephanie Dippel; Tawan Imvised; Faikah Gueler; Benno M Ure; Jochen F Kuebler; Christian Klemann
Journal:  PLoS One       Date:  2017-07-13       Impact factor: 3.240

Review 6.  From rabbit antibody repertoires to rabbit monoclonal antibodies.

Authors:  Justus Weber; Haiyong Peng; Christoph Rader
Journal:  Exp Mol Med       Date:  2017-03-24       Impact factor: 8.718

7.  Myeloid-derived suppressor cells are bound and inhibited by anti-thymocyte globulin.

Authors:  Young Suk Lee; Eduardo Davila; Tianshu Zhang; Hugh P Milmoe; Stefanie N Vogel; Jonathan S Bromberg; Joseph R Scalea
Journal:  Innate Immun       Date:  2019-01       Impact factor: 2.680

8.  Precision Medicine in Kidney Transplantation: Just Hype or a Realistic Hope?

Authors:  Ehsan Nobakht; Muralidharan Jagadeesan; Rohan Paul; Jonathan Bromberg; Sherry Dadgar
Journal:  Transplant Direct       Date:  2021-01-07

9.  Non-genotoxic conditioning facilitates hematopoietic stem cell gene therapy for hemophilia A using bioengineered factor VIII.

Authors:  Athena L Russell; Chengyu Prince; Taran S Lundgren; Kristopher A Knight; Gabriela Denning; Jordan S Alexander; Jaquelyn T Zoine; H Trent Spencer; Shanmuganathan Chandrakasan; Christopher B Doering
Journal:  Mol Ther Methods Clin Dev       Date:  2021-05-05       Impact factor: 6.698

  9 in total

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