Literature DB >> 18795259

Acute respiratory failure after aspiration of activated charcoal with recurrent deposition and release from an intrapulmonary cavern.

Roland C E Francis1, Joerg C Schefold, Sven Bercker, Bettina Temmesfeld-Wollbrück, Wilko Weichert, Claudia D Spies, Steffen Weber-Carstens.   

Abstract

OBJECTIVE: To report on the recurrent release of charcoal from an intrapulmonary cavern in a case of acute respiratory failure after charcoal aspiration.
DESIGN: Case report.
SETTING: Anaesthesiological ICU, university hospital. PATIENT: An 18-year-old ethanol intoxicated comatose patient regurgitated and aspirated activated charcoal during orotracheal intubation. TREATMENT: After 2 days of mechanical ventilation, the patient was transferred to a tertiary care university hospital. On admission, acute respiratory distress syndrome with bilateral pulmonary infiltrations was diagnosed. The patient's recovery was hampered by recurrent release of charcoal from an intrapulmonary cavern. Sophisticated ventilatory support, prone positioning, secretolytics, repetitive bronchoscopy, and antibiotic therapy may have facilitated bronchoalveolar clearance and weaning after 18 days.
CONCLUSION: Aspiration may be a dramatic complication if charcoal is administered in comatose patients without airway protection. In this case report, advanced intensive care measures were necessary to tackle the special feature of charcoal release from an intrapulmonary cavern.

Entities:  

Mesh:

Substances:

Year:  2008        PMID: 18795259     DOI: 10.1007/s00134-008-1259-5

Source DB:  PubMed          Journal:  Intensive Care Med        ISSN: 0342-4642            Impact factor:   17.440


  18 in total

1.  Application of pharmacokinetic-pharmacodynamic modelling in management of QT abnormalities after citalopram overdose.

Authors:  Geoffrey K Isbister; Lena E Friberg; Stephen B Duffull
Journal:  Intensive Care Med       Date:  2006-05-10       Impact factor: 17.440

Review 2.  Position statement and practice guidelines on the use of multi-dose activated charcoal in the treatment of acute poisoning. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists.

Authors: 
Journal:  J Toxicol Clin Toxicol       Date:  1999

3.  Incidence, risk factors, and outcome of aspiration pneumonitis in ICU overdose patients.

Authors:  Andreas Christ; Christian A Arranto; Christian Schindler; Theresia Klima; Patrick R Hunziker; Martin Siegemund; Stephan C Marsch; Urs Eriksson; Christian Mueller
Journal:  Intensive Care Med       Date:  2006-07-07       Impact factor: 17.440

4.  Severe respiratory failure following charcoal application in a toddler.

Authors:  J Golej; H Boigner; G Burda; M Hermon; G Trittenwein
Journal:  Resuscitation       Date:  2001-06       Impact factor: 5.262

Review 5.  Position paper: Single-dose activated charcoal.

Authors:  P A Chyka; D Seger; E P Krenzelok; J A Vale
Journal:  Clin Toxicol (Phila)       Date:  2005       Impact factor: 4.467

6.  Pressure-controlled ventilation attenuates lung microvascular injury in a rat model of activated charcoal aspiration.

Authors:  Thomas C Arnold; Shu Zhang; Feng Xiao; Steven A Conrad; Donna L Carden
Journal:  J Toxicol Clin Toxicol       Date:  2003

Review 7.  Bronchiolitis: the pathologist's perspective.

Authors:  Daniel W Visscher; Jeffrey L Myers
Journal:  Proc Am Thorac Soc       Date:  2006

Review 8.  Misadventures with activated charcoal and recommendations for safe use.

Authors:  L S Mauro; J J Nawarskas; V F Mauro
Journal:  Ann Pharmacother       Date:  1994 Jul-Aug       Impact factor: 3.154

Review 9.  Beta-adrenoceptor responses of the airways: for better or worse?

Authors:  Kenneth J Broadley
Journal:  Eur J Pharmacol       Date:  2006-02-15       Impact factor: 4.432

10.  Prone ventilation following witnessed pulmonary aspiration: the effect on oxygenation.

Authors:  Jason Easby; Babu K Abraham; Stephen M Bonner; Stephen Graham
Journal:  Intensive Care Med       Date:  2003-08-28       Impact factor: 17.440

View more
  3 in total

1.  The therapeutic effects of anti-oxidant and anti-inflammatory drug quercetin on aspiration-induced lung injury in rats.

Authors:  Mehmet Ziya Yilmaz; Aygul Guzel; Aysun Caglar Torun; Ali Okuyucu; Osman Salis; Rifat Karli; Ayhan Gacar; Tolga Guvenc; Sule Paksu; Volkan Urey; Naci Murat; Hasan Alacam
Journal:  J Mol Histol       Date:  2013-10-13       Impact factor: 2.611

Review 2.  Activated charcoal for acute overdose: a reappraisal.

Authors:  David N Juurlink
Journal:  Br J Clin Pharmacol       Date:  2015-11-09       Impact factor: 4.335

3.  Year in review in Intensive Care Medicine 2009: II. Neurology, cardiovascular, experimental, pharmacology and sedation, communication and teaching.

Authors:  Massimo Antonelli; Elie Azoulay; Marc Bonten; Jean Chastre; Giuseppe Citerio; Giorgio Conti; Daniel De Backer; François Lemaire; Herwig Gerlach; Goran Hedenstierna; Michael Joannidis; Duncan Macrae; Jordi Mancebo; Salvatore M Maggiore; Alexandre Mebazaa; Jean-Charles Preiser; Jerôme Pugin; Jan Wernerman; Haibo Zhang
Journal:  Intensive Care Med       Date:  2010-01-28       Impact factor: 17.440

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.