Literature DB >> 18794219

Evidence of increased motoneuron excitability in stroke patients without clinical spasticity.

Jakob Udby Blicher1, Jørgen Feldbaek Nielsen.   

Abstract

INTRODUCTION: The contribution of hyperreflexia to impairment after stroke is debated. Spinal motoneuron excitability in healthy subjects and stroke patients with and without spasticity was compared.
METHODS: Twenty-four patients with single stroke more than 6 months ago and 18 gender-matched healthy volunteers were included. Spasticity was assessed according to the Modified Ashworth Scale. Mmax amplitude and F wave frequency in the abductor pollicis brevis muscle were measured by electrical stimulation of the median nerve.
RESULTS: Mmax values were comparable between the groups. However, patients with (n=7) and without (n=17) clinically evident spasticity had a significant increase in F wave frequency when compared with healthy subjects. F wave frequency did not differ between spastic and nonspastic patients. DISCUSSION: Increase in spinal motoneuron excitability after stroke is present in stroke patients with minor or no motor deficiencies and does not necessarily lead to spasticity.

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Year:  2008        PMID: 18794219     DOI: 10.1177/1545968308317439

Source DB:  PubMed          Journal:  Neurorehabil Neural Repair        ISSN: 1545-9683            Impact factor:   3.919


  2 in total

1.  The origins of neuromuscular fatigue post-stroke.

Authors:  S Knorr; T D Ivanova; T J Doherty; J A Campbell; S J Garland
Journal:  Exp Brain Res       Date:  2011-08-17       Impact factor: 1.972

2.  Differential Changed Excitability of Spinal Motor Neurons Innervating Tibialis Anterior and Peroneus Muscles Cause Foot Inversion After Stroke.

Authors:  Gang Liu; Chin-Hsuan Chia; Yue Cao; Xin-Wei Tang; Shan Tian; Xue-Yan Shen; Ying Chen; Rong-Rong Lu; Jun-Fa Wu; Yi Wu
Journal:  Front Neurol       Date:  2020-11-24       Impact factor: 4.003

  2 in total

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