Literature DB >> 18793773

Feasibility, safety, and efficacy of conservative laparoscopic treatment of borderline ovarian tumors.

Raffaele Tinelli1, Mario Malzoni, Francesco Cosentino, Ciro Perone, Andrea Tinelli, Antonio Malvasi, Ettore Cicinelli.   

Abstract

OBJECTIVE: To outline the most recent information regarding conservative laparoscopic surgery for young women with borderline ovarian tumors.
DESIGN: Review article.
SETTING: Advanced Gynecological Endoscopy Center, Malzoni Medical Center, Avellino, Italy. PATIENT(S): Young women with low-stage borderline ovarian tumors who wish to preserve their fertility. INTERVENTION(S): Conservative laparoscopic surgery with unilateral salpingo-oophorectomy or cystectomy. MAIN OUTCOME MEASURE(S): Recurrence rate and outcomes. RESULT(S): Laparoscopic cystectomy may have more chance of preserving a woman's fertility compared with adnexectomy because of the removal of less ovarian tissue. Its greatest danger is the risk of inadvertently leaving behind some malignant cells. Therefore, this procedure should be reserved for patients with previous unilateral salpingo-oophorectomy or when bilateral lesions are present to preserve at least some ovarian tissue. CONCLUSION(S): When borderline ovarian tumors are identified at surgery by intraoperative histology, the recommended conservative treatment should be laparoscopic salpingo-oophorectomy. Recurrence can be noted after this type of treatment, but the cases of recurrent disease can be detected with close follow-up and treated accordingly. For these reasons, careful selection of candidates for this kind of treatment is, of course, necessary and close follow-up is required. If these restrictions are rigorously applied, then fertility-sparing surgery may be considered a safe option for this pathology, but all laparoscopic procedures should be reserved for oncologic surgeons trained in extensive laparoscopic procedures.

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Year:  2008        PMID: 18793773     DOI: 10.1016/j.fertnstert.2008.07.1716

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  6 in total

1.  Risk factors for recurrence of ovarian borderline tumors.

Authors:  K K Shih; Q Zhou; J Huh; J C Morgan; A Iasonos; C Aghajanian; D S Chi; R R Barakat; N R Abu-Rustum
Journal:  Gynecol Oncol       Date:  2010-12-10       Impact factor: 5.482

Review 2.  Role of minimally invasive surgery in staging of ovarian cancer.

Authors:  David A Iglesias; Pedro T Ramirez
Journal:  Curr Treat Options Oncol       Date:  2011-09

Review 3.  Management, prognosis and reproductive outcomes of borderline ovarian tumor relapse during pregnancy: from diagnosis to potential treatment options.

Authors:  Francesco Cosentino; Luigi Carlo Turco; Stefano Cianci; Francesco Fanfani; Anna Fagotti; Salvatore Gueli Alletti; Giuseppe Vizzielli; Salvatore Giovanni Vitale; Antonio Simone Laganà; Francesco Padula; Claudio Coco; Salvatore Pisconti; Giovanni Scambia
Journal:  J Prenat Med       Date:  2016 Jan-Jun

4.  Quality of life and sexual function in patients with borderline tumors of the ovary. A substudy of the Arbeitsgemeinschaft Gynaekologische Onkologie (AGO) study group ROBOT study.

Authors:  Juliane Farthmann; Annette Hasenburg; Meike Weil; Christina Fotopoulou; Nina Ewald-Riegler; Oya du Bois; Fabian Trillsch; Sven Mahner; Hans-Georg Strauss; Pauline Wimberger; Alexander Reuss; Andreas du Bois
Journal:  Support Care Cancer       Date:  2014-07-05       Impact factor: 3.603

5.  Borderline ovarian tumors: clinical characteristics, management, and outcomes - a multicenter study.

Authors:  Mehmet Gokcu; Kemal Gungorduk; Osman Aşıcıoğlu; Nilüfer Çetinkaya; Tayfun Güngör; Gonca Pakay; Zeliha Fırat Cüylan; Tayfun Toptaş; Ramazan Özyurt; Elif Ağaçayak; Aykut Ozdemir; Onur Erol; Anıl Turan; Varol Gülseren; Mehmet Sait İcen; Taylan Şenol; Hakan Güraslan; Burcu Yücesoy; Ahmet Sahbaz; Ozgu Gungorduk; Berhan Besimoğlu; Kaan Pakay; Osman Temizkan; Muzaffer Sancı; Tayup Şimşek; Mehmet Mutlu Meydanlı; Mehmet Harma; Levent Yaşar; Birtan Boran; Aysel Derbent Uysal; Ateş Karateke
Journal:  J Ovarian Res       Date:  2016-10-18       Impact factor: 4.234

6.  The safety of fertility and ipsilateral ovary procedures for borderline ovarian tumors.

Authors:  Tong Lou; Fang Yuan; Ying Feng; Shuzhen Wang; Huimin Bai; Zhenyu Zhang
Journal:  Oncotarget       Date:  2017-12-06
  6 in total

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