| Literature DB >> 18792424 |
Hiroaki Sugiyama1, Kazuhisa Maeda, Masayuki Yamato, Ryuhei Hayashi, Takeshi Soma, Yasutaka Hayashida, Joseph Yang, Masayuki Shirakabe, Akifumi Matsuyama, Akihiko Kikuchi, Yoshiki Sawa, Teruo Okano, Yasuo Tano, Kohji Nishida.
Abstract
We examined a novel human feeder cell layer of mesenchymal stem cells harvested from human adipose tissues. Gene expression analyses and colony-forming assay with human primary epithelial cells showed that the adipose tissue-derived mesenchymal stem cells produced various factors to support epithelial stem/progenitor maintenance and cell growth. Using the mesenchymal stem cells as novel feeder layers, transplantable epithelial cell sheets could be effectively generated ex vivo on temperature-responsive cell-culture surfaces. Copyright (c) 2008 John Wiley & Sons, Ltd.Entities:
Mesh:
Year: 2008 PMID: 18792424 DOI: 10.1002/term.111
Source DB: PubMed Journal: J Tissue Eng Regen Med ISSN: 1932-6254 Impact factor: 3.963