Literature DB >> 1879050

Comparative intraperitoneal pharmacokinetics of three platinum analogues.

M J Lind1, D J Murphy, H Sharma, N Tinker, A Smith, C A McAuliffe, D Crowther.   

Abstract

The pharmakokinetic profiles of intraperitoneally infused platinum analogues were determined in 13 women exhibiting minimal residual disease following surgery and systemic chemotherapy for epithelial ovarian cancer or fallopian tube carcinoma by following the disposition of tracer doses of 195mPt radiolabel. Six patients received iproplatin, four were given cisplatin and three received carboplatin. The present data demonstrate no difference in the disposition of total platinum between these three analogues, but differences in the kinetics of free platinum may exist.

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Year:  1991        PMID： 1879050     DOI： 10.1007/bf00685543

Source DB:  PubMed          Journal:  Cancer Chemother Pharmacol        ISSN： 0344-5704            Impact factor:   3.333


  9 in total

1.  Long-term results of a cisplatin-containing combination chemotherapy regimen for the treatment of advanced ovarian carcinoma.

Authors:  K G Louie; R F Ozols; C E Myers; Y Ostchega; J Jenkins; D Howser; R C Young
Journal:  J Clin Oncol       Date:  1986-11       Impact factor: 44.544

Review 2.  Chemotherapy of ovarian cancer.

Authors:  R F Ozols; R C Young
Journal:  Semin Oncol       Date:  1984-09       Impact factor: 4.929

3.  Pharmacokinetic rationale for peritoneal drug administration in the treatment of ovarian cancer.

Authors:  R L Dedrick; C E Myers; P M Bungay; V T DeVita
Journal:  Cancer Treat Rep       Date:  1978-01

4.  Experimental and clinical results with intraperitoneal cisplatin.

Authors:  W W ten Bokkel Huinink; R Dubbelman; E Aartsen; H Franklin; J G McVie
Journal:  Semin Oncol       Date:  1985-09       Impact factor: 4.929

5.  In vitro plasma binding of some second generation antitumor platinum complexes.

Authors:  R Momburg; M Bourdeaux; M Sarrazin; F Roux; C Briand
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1985 Jan-Mar       Impact factor: 2.441

6.  Second-look laparotomy in the management of epithelial ovarian carcinoma: an evaluation of fifty cases.

Authors:  D M Luesley; K K Chan; J W Fielding; R Hurlow; G R Blackledge; J A Jordon
Journal:  Obstet Gynecol       Date:  1984-09       Impact factor: 7.661

7.  Cisplatin combination chemotherapy versus chlorambucil in advanced ovarian carcinoma: mature results of a randomized trial.

Authors:  C J Williams; G M Mead; F R Macbeth; J Thompson; J M Whitehouse; H MacDonald; V J Harvey; M L Slevin; T A Lister; J H Shepherd
Journal:  J Clin Oncol       Date:  1985-11       Impact factor: 44.544

8.  Microscale syntheses of anti-tumour platinum compounds labelled with 191Pt.

Authors:  J Baer; R Harrison; C A McAuliffe; A Zaki; H L Sharma; A G Smith
Journal:  Int J Appl Radiat Isot       Date:  1985-03

9.  Preclinical studies identifying carboplatin as a viable cisplatin alternative.

Authors:  K R Harrap
Journal:  Cancer Treat Rev       Date:  1985-09       Impact factor: 12.111
  9 in total
  1 in total

1.  Phase I clinical and pharmacological study of intraperitoneal cis-bis-neodecanoato( trans- R, R-1, 2-diaminocyclohexane)-platinum II entrapped in multilamellar liposome vesicles.

Authors:  C F Verschraegen; S Kumagai; R Davidson; B Feig; P Mansfield; S J Lee; D S Maclean; W Hu; A R Khokhar; Z H Siddik
Journal:  J Cancer Res Clin Oncol       Date:  2003-08-29       Impact factor: 4.553
  1 in total

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