BACKGROUND: This study evaluated the relationship between neuroticism (N), a probable risk factor for emotional disorders, and modulation of startle reflexes (SRs). METHODS: One hundred thirty-two adolescents with varying levels of N but without anxiety or depressive disorders were evaluated in contextual cue and explicit threat cue paradigms. RESULTS: Within the explicit threat cue paradigm, N potentiated SRs more in conditions that were intermediately associated with threat of an aversive biceps contraction than conditions that were the furthest from and conditions that were the closest to the same threat. Also, N potentiated SRs across the entire experiment, regardless of experimental conditions, in male and not in female subjects. CONCLUSIONS: These results suggest that adolescents with high levels of N show greater sensitivity to contexts intermediately associated with threat. Results are discussed in comparison with other studies of groups at risk for anxiety and depressive disorders.
BACKGROUND: This study evaluated the relationship between neuroticism (N), a probable risk factor for emotional disorders, and modulation of startle reflexes (SRs). METHODS: One hundred thirty-two adolescents with varying levels of N but without anxiety or depressive disorders were evaluated in contextual cue and explicit threat cue paradigms. RESULTS: Within the explicit threat cue paradigm, N potentiated SRs more in conditions that were intermediately associated with threat of an aversive biceps contraction than conditions that were the furthest from and conditions that were the closest to the same threat. Also, N potentiated SRs across the entire experiment, regardless of experimental conditions, in male and not in female subjects. CONCLUSIONS: These results suggest that adolescents with high levels of N show greater sensitivity to contexts intermediately associated with threat. Results are discussed in comparison with other studies of groups at risk for anxiety and depressive disorders.
Authors: Lynne Lieberman; Huiting Liu; Ashley A Huggins; Andrea C Katz; Michael J Zvolensky; Stewart A Shankman Journal: Psychophysiology Date: 2016-06-08 Impact factor: 4.016
Authors: Alexander J Shackman; Do P M Tromp; Melissa D Stockbridge; Claire M Kaplan; Rachael M Tillman; Andrew S Fox Journal: Psychol Bull Date: 2016-10-10 Impact factor: 17.737
Authors: Michelle G Craske; Kate B Wolitzky-Taylor; Susan Mineka; Richard Zinbarg; Allison M Waters; Suzanne Vrshek-Schallhorn; Alyssa Epstein; Bruce Naliboff; Edward Ornitz Journal: J Abnorm Psychol Date: 2011-10-10
Authors: Allison M Waters; Maria Nazarian; Susan Mineka; Richard E Zinbarg; James W Griffith; Bruce Naliboff; Edward M Ornitz; Michelle G Craske Journal: Psychiatry Res Date: 2014-02-05 Impact factor: 3.222
Authors: Tyson V Barker; Bethany Reeb-Sutherland; Kathryn A Degnan; Olga L Walker; Andrea Chronis-Tuscano; Heather A Henderson; Daniel S Pine; Nathan A Fox Journal: Psychophysiology Date: 2015-09-02 Impact factor: 4.016