Literature DB >> 18788965

Dying with advanced dementia in long-term care geriatric institutions: a retrospective study.

Paola Di Giulio1, Franco Toscani, Daniele Villani, Cinzia Brunelli, Simona Gentile, Patrizia Spadin.   

Abstract

OBJECTIVE: The aim of this study is to describe the last month of life of severely demented elders in long-term care institutions, and the clinical decisions in the management of their end-of-life events.
DESIGN: Retrospective exploratory study.
SETTING: Seven Italian long-term care institutions with more than 200 beds. PARTICIPANTS: One hundred forty-one patients with advanced (FAST stage = 7c) dementia (Alzheimer disease, vascular, other kinds of dementia, severe cognitive impairment). MEASUREMENT: Diagnosis, Mini-Mental State Examination, cause of death. Data were collected from clinical and nursing records referring to the last 30 days of life: symptoms and signs, intensity and incidence, treatments (antibiotics, analgesics, anxiolytics, antidepressants, artificial nutrition/hydration, and use of restraints); the last 48 hours: cardiopulmonary resuscitation attempts and life-sustaining drugs.
RESULTS: Patients were given antibiotics (71.6%), anxiolytics (37.1%), and antidepressants (7.8%). Twenty-nine patients (20.5%) were tube- or percutaneous endoscopic gastrostomy (PEG)-fed. Most patients (66.6%) were also parenterally hydrated (72 intravenously, 15 by hypodermoclysis). Some form of physical restraint was used for 58.2% (bed-rails and other immobilizers). Almost half of the patients had pressure sores. In general, attention to physical suffering was fairly good, but during the last 48 hours a number of interventions could be considered inappropriate for these patients: tube feeding (20.5%), intravenous hydration (66.6%), antibiotics (71.6%), and life-sustaining drugs (34.0%).
CONCLUSIONS: Some indicators imply a less than optimal quality of care (restraints, pressure sores, psychoactive drugs, and the lack of documentation of shared decision-making) and suggest that far advanced demented patients are not fully perceived as "terminal."

Entities:  

Mesh:

Year:  2008        PMID: 18788965     DOI: 10.1089/jpm.2008.0020

Source DB:  PubMed          Journal:  J Palliat Med        ISSN: 1557-7740            Impact factor:   2.947


  34 in total

Review 1.  Antibiotic use and associated factors in patients with dementia: a systematic review.

Authors:  Tessa van der Maaden; Simone A Hendriks; Henrica C W de Vet; Menno T Zomerhuis; Martin Smalbrugge; Elise P Jansma; Raymond T C M Koopmans; Cees M P M Hertogh; Jenny T van der Steen
Journal:  Drugs Aging       Date:  2015-01       Impact factor: 3.923

2.  Palliative care for patients with dementia: a national survey.

Authors:  Alexia M Torke; Laura R Holtz; Siu Hui; Peter Castelluccio; Stephen Connor; Matthew A Eaton; Greg A Sachs
Journal:  J Am Geriatr Soc       Date:  2010-11       Impact factor: 5.562

3.  Advanced dementia: state of the art and priorities for the next decade.

Authors:  Susan L Mitchell; Betty S Black; Mary Ersek; Laura C Hanson; Susan C Miller; Greg A Sachs; Joan M Teno; R Sean Morrison
Journal:  Ann Intern Med       Date:  2012-01-03       Impact factor: 25.391

4.  Is tube feeding futile in advanced dementia?

Authors:  Matthew C Lynch
Journal:  Linacre Q       Date:  2016-08

5.  Mapping health status measures to a utility measure in a study of nursing home residents with advanced dementia.

Authors:  Keith S Goldfeld; Mary Beth Hamel; Susan L Mitchell
Journal:  Med Care       Date:  2012-05       Impact factor: 2.983

6.  Dying with dementia: symptom burden, quality of care, and place of death.

Authors:  Luis Carlos Escobar Pinzon; Matthias Claus; Klaus Maria Perrar; Kirsten Isabel Zepf; Stephan Letzel; Martin Weber
Journal:  Dtsch Arztebl Int       Date:  2013-03-22       Impact factor: 5.594

7.  Preparedness for Death: How Caregivers of Elders With Dementia Define and Perceive its Value.

Authors:  Cynthia A Hovland-Scafe; Betty J Kramer
Journal:  Gerontologist       Date:  2017-11-10

8.  The clinical course of advanced dementia.

Authors:  Susan L Mitchell; Joan M Teno; Dan K Kiely; Michele L Shaffer; Richard N Jones; Holly G Prigerson; Ladislav Volicer; Jane L Givens; Mary Beth Hamel
Journal:  N Engl J Med       Date:  2009-10-15       Impact factor: 91.245

Review 9.  Decision making about change of medication for comorbid disease at the end of life: an integrative review.

Authors:  Ronald T C M van Nordennen; Jan C M Lavrijsen; Kris C P Vissers; Raymond T C M Koopmans
Journal:  Drugs Aging       Date:  2014-07       Impact factor: 3.923

10.  The cost-effectiveness of the decision to hospitalize nursing home residents with advanced dementia.

Authors:  Keith S Goldfeld; Mary Beth Hamel; Susan L Mitchell
Journal:  J Pain Symptom Manage       Date:  2013-04-06       Impact factor: 3.612

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