Literature DB >> 18787737

Macrolide use shortens fever duration in Mycoplasma pneumoniae infection in children: a 2-year experience.

Ying-Jen Lu1, Tou-Hwei Chen, Lung-Huang Lin, Chung-Min Shen, Ceng-Hua Huang.   

Abstract

BACKGROUND AND
PURPOSE: Mycoplasma pneumoniae infection is a major cause of community-acquired respiratory tract infection in children. We performed a retrospective study to evaluate clinical and demographic data and compare outcomes with and without macrolide treatment in children with M. pneumoniae infection.
METHODS: A total of 139 patients were included in the study and classified into two groups according to whether or not they received macrolide therapy during hospitalization. Data collected included demographic, clinical and laboratory characteristics.
RESULTS: Cases were most prevalent during September. Fever and cough were the most common presenting symptoms/signs. The time to fever subsidence did not differ significantly between azithromycin and erythromycin usage. We also found significantly longer fever duration in the group without macrolide usage.
CONCLUSION: Treatment with macrolide shortens fever duration of M. pneumoniae infection in children.

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Year:  2008        PMID: 18787737

Source DB:  PubMed          Journal:  J Microbiol Immunol Infect        ISSN: 1684-1182            Impact factor:   4.399


  2 in total

1.  Rapid mycoplasma culture for the early diagnosis of Mycoplasma pneumoniae infection.

Authors:  Ling-di Ma; Baojin Chen; Yanfen Dong; Jing Fan; Lei Xia; Shi-zhong Wang; Qian Liu; Lijia Jiang
Journal:  J Clin Lab Anal       Date:  2010       Impact factor: 2.352

2.  The timing of azithromycin treatment is not associated with the clinical prognosis of childhood Mycoplasma pneumoniae pneumonia in high macrolide-resistant prevalence settings.

Authors:  Dehua Yang; Linghong Chen; Zhimin Chen
Journal:  PLoS One       Date:  2018-01-29       Impact factor: 3.240

  2 in total

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