Literature DB >> 18787543

Germline MC1R variants and BRAF mutant melanoma.

Elke Hacker1, Nicholas K Hayward.   

Abstract

Recent studies have demonstrated that melanocortin-1 receptor (MC1R) variants increase the risk of melanomas harboring BRAF mutations. This finding provides insight into the relationship between host genotype and selection for somatic mutation type. Additional larger studies are required in diverse populations to further examine the interaction between MC1R and BRAF in different melanoma subtypes.

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Year:  2008        PMID： 18787543     DOI： 10.1038/jid.2008.236

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


  3 in total

1.  Melanoma: Molecular Pathogenesis and Therapeutic Management.

Authors:  Yuxin Liu; M Saeed Sheikh
Journal:  Mol Cell Pharmacol       Date:  2014

2.  Molecular markers of tumor progression in melanoma.

Authors:  Joshua Rother; Dan Jones
Journal:  Curr Genomics       Date:  2009-06       Impact factor: 2.236

3.  MC1R variants and cutaneous melanoma risk according to histological type, body site, and Breslow thickness: a pooled analysis from the M-SKIP project.

Authors:  Saverio Caini; Sara Gandini; Francesca Botta; Elena Tagliabue; Sara Raimondi; Eduardo Nagore; Ines Zanna; Patrick Maisonneuve; Julia Newton-Bishop; David Polsky; DeAnn Lazovich; Rajiv Kumar; Peter A Kanetsky; Veronica Hoiom; Paola Ghiorzo; Maria Teresa Landi; Gloria Ribas; Chiara Menin; Alexander J Stratigos; Giuseppe Palmieri; Gabriella Guida; Jose Carlos García-Borrón; Hongmei Nan; Julian Little; Francesco Sera; Susana Puig; Maria Concetta Fargnoli
Journal:  Melanoma Res       Date:  2020-10       Impact factor: 3.199
  3 in total

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