| Literature DB >> 18786583 |
Ruthann Nichols1, Jonathan P Egle, Nicholas R Langan, Gregory C Palmer.
Abstract
Sulfakinins are myoactive peptides and antifeedant factors. Naturally occurring drosulfakinin I (DSK I; FDDYGHMRFNH(2)) and drosulfakinin II (DSK II; GGDDQFDDYGHMRFNH(2)) contain sulfated or nonsulfated tyrosine. We discovered sDSK II and nsDSK II influenced Drosophila melanogaster larval odor preference. However, sDSK I, nsDSK I, MRFNH(2), and saline did not influence odor preference. We discovered sDSK I and nsDSK I influenced larval locomotion. However, sDSK II, nsDSK II, MRFNH(2), and saline did not influence locomotion. Our novel data suggest distinct mechanisms underlie the effects of DSK I and DSK II peptides on odor preference and locomotion, parameters important to many facets of animal survival.Entities:
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Year: 2008 PMID： 18786583 PMCID： PMC3430133 DOI： 10.1016/j.peptides.2008.08.010
Source DB: PubMed Journal: Peptides ISSN： 0196-9781 Impact factor: 3.750