Literature DB >> 18784904

Formulations for delivery of therapeutic proteins.

Snjezana Stolnik1, Kevin Shakesheff.   

Abstract

Advances in biotechnology have now created a capacity to produce therapeutically active proteins on a commercial scale, opening the potential for their application in an array of disease conditions. The process of translation of the variety of different therapeutic proteins into the medicines used in clinics is now occurring. To assist in this translation, new formulations to deliver proteins could play an important role. These new formulations need to more adequately address the pharmacological and therapeutic requirement for each particular protein/peptide and, in that way, either improve present therapies or extend with new entries the current list of protein based medicines used in clinic.

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Year:  2008        PMID: 18784904     DOI: 10.1007/s10529-008-9834-y

Source DB:  PubMed          Journal:  Biotechnol Lett        ISSN: 0141-5492            Impact factor:   2.461


  6 in total

1.  Improved mucoadhesion and cell uptake of chitosan and chitosan oligosaccharide surface-modified polymer nanoparticles for mucosal delivery of proteins.

Authors:  Sathish Dyawanapelly; Uday Koli; Vimisha Dharamdasani; Ratnesh Jain; Prajakta Dandekar
Journal:  Drug Deliv Transl Res       Date:  2016-08       Impact factor: 4.617

2.  Oral Delivery of Teriparatide Using a Nanoemulsion System: Design, in Vitro and in Vivo Evaluation.

Authors:  Bashar M Altaani; Ammar M Almaaytah; Suha Dadou; Khouloud Alkhamis; Mousa H Daradka; Wael Hananeh
Journal:  Pharm Res       Date:  2020-04-06       Impact factor: 4.200

Review 3.  Bioreducible polycations as shuttles for therapeutic nucleic acid and protein transfection.

Authors:  Philipp M Klein; Ernst Wagner
Journal:  Antioxid Redox Signal       Date:  2014-01-08       Impact factor: 8.401

4.  Conformation and dynamics of biopharmaceuticals: transition of mass spectrometry-based tools from academe to industry.

Authors:  Igor A Kaltashov; Cedric E Bobst; Rinat R Abzalimov; Steven A Berkowitz; Damian Houde
Journal:  J Am Soc Mass Spectrom       Date:  2009-10-29       Impact factor: 3.109

5.  Mechanism of mucosal permeability enhancement of CriticalSorb® (Solutol® HS15) investigated in vitro in cell cultures.

Authors:  Saif Shubber; Driton Vllasaliu; Cyril Rauch; Faron Jordan; Lisbeth Illum; Snjezana Stolnik
Journal:  Pharm Res       Date:  2014-09-05       Impact factor: 4.200

Review 6.  Nasal delivery of high molecular weight drugs.

Authors:  Yildiz Ozsoy; Sevgi Gungor; Erdal Cevher
Journal:  Molecules       Date:  2009-09-23       Impact factor: 4.411

  6 in total

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