Literature DB >> 18783263

Streptavidin reduces oxygen quenching of biotinylated ruthenium(II) and palladium(II) complexes.

T Soller1, M Ringler, M Wunderlich, T A Klar, J Feldmann, H-P Josel, J Koci, Y Markert, A Nichtl, K Kürzinger.   

Abstract

Transition metal complexes such as biotinylated ruthenium(II) tris(bipyridyl) and palladium(II) porphyrin show an increase in luminescence intensity and lifetime upon binding to streptavidin in aqueous solution. Here we show that this increase of luminescence lifetime and intensity are caused by the shielding of the transition metal complexes from dissolved oxygen through streptavidin rather than by hydrophobicity effects as recently claimed.

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Year:  2008        PMID: 18783263     DOI: 10.1021/jp8044065

Source DB:  PubMed          Journal:  J Phys Chem B        ISSN: 1520-5207            Impact factor:   2.991


  1 in total

1.  Flexibility of a biotinylated ligand in artificial metalloenzymes based on streptavidin--an insight from molecular dynamics simulations with classical and ab initio force fields.

Authors:  Jarosław J Panek; Thomas R Ward; Aneta Jezierska-Mazzarello; Marjana Novic
Journal:  J Comput Aided Mol Des       Date:  2010-06-05       Impact factor: 3.686

  1 in total

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