Literature DB >> 1878124

Phospholipase A2--a mediator between proximal and distal effectors of inflammation.

W Pruzanski1, P Vadas.   

Abstract

Phospholipase A2 (PLA2) is known to play an important intracellular role in inflammatory processes but does it also perform a vital function extracellularly? Here, W. Pruzanski and P. Vadas marshall the evidence supporting PLA2 as a mediator of inflammation, specifically in linking local and systemic effects.

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Year:  1991        PMID: 1878124     DOI: 10.1016/S0167-5699(05)80042-8

Source DB:  PubMed          Journal:  Immunol Today        ISSN: 0167-5699


  65 in total

1.  Inhibitory Effect of FXa on Secretory Group IIA Phospholipase A2.

Authors:  Sae-Kwang Ku; Jong-Sup Bae
Journal:  Inflammation       Date:  2015       Impact factor: 4.092

2.  Purification and inhibitory profile of phospholipase A2 inhibitors from Australian elapid sera.

Authors:  P G Hains; K W Broady
Journal:  Biochem J       Date:  2000-02-15       Impact factor: 3.857

Review 3.  Cancer evolution and individual susceptibility.

Authors:  Jesús Pérez-Losada; Andrés Castellanos-Martín; Jian-Hua Mao
Journal:  Integr Biol (Camb)       Date:  2011-01-24       Impact factor: 2.192

4.  Alterations in the activity of phospholipases A2 in postmortem white matter from patients with multiple sclerosis.

Authors:  S J Huterer; W W Tourtellotte; J R Wherrett
Journal:  Neurochem Res       Date:  1995-11       Impact factor: 3.996

Review 5.  C-reactive protein as a pro-inflammatory mediator in cardiovascular disease by its ability to activate complement: additional proof and hypothetical mechanisms.

Authors:  W K Lagrand; R Nijmeijer; H W M Niessen; C A Visser; W Th Hermens; C E Hack
Journal:  Neth Heart J       Date:  2002-04       Impact factor: 2.380

6.  Platelet-activating factor and phospholipase A2 in patients with septic shock and trauma.

Authors:  J Sörensen; B Kald; C Tagesson; M Lindahl
Journal:  Intensive Care Med       Date:  1994-11       Impact factor: 17.440

7.  Phospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizations.

Authors:  Saida Mebarek; Abdelkarim Abousalham; David Magne; Le Duy Do; Joanna Bandorowicz-Pikula; Slawomir Pikula; René Buchet
Journal:  Int J Mol Sci       Date:  2013-03-01       Impact factor: 5.923

8.  The role of human adenovirus early region 3 proteins (gp19K, 10.4K, 14.5K, and 14.7K) in a murine pneumonia model.

Authors:  T E Sparer; R A Tripp; D L Dillehay; T W Hermiston; W S Wold; L R Gooding
Journal:  J Virol       Date:  1996-04       Impact factor: 5.103

9.  Elevated expression of human nonpancreatic phospholipase A2 in psoriatic tissue.

Authors:  S Andersen; W Sjursen; A Laegreid; G Volden; B Johansen
Journal:  Inflammation       Date:  1994-02       Impact factor: 4.092

10.  Cytosolic phospholipase A2 from human monocytic cells: characterization of substrate specificity and Ca(2+)-dependent membrane association.

Authors:  W Rehfeldt; K Resch; M Goppelt-Struebe
Journal:  Biochem J       Date:  1993-07-01       Impact factor: 3.857

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